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> L-FABP (FABP1) L-FABP (FABP1)
L-FABP binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm. L-FABP may be involved in intracellular lipid transport.
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L-FABP Proteins
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L-FABP (FABP1) Related Areas
Cardiovascular>>Lipid Metabolism>>L-FABP/FABP1
L-FABP (FABP1) Related Pathways
L-FABP (FABP1) Alternative Names
L-FABP, FABP1, FABPL [Homo sapiens]
L-FABP, Fabpl, L-FABP, MGC13855 [Mus musculus]
Summaries for L-FABP (FABP1)
Entrez Gene summary for FABP1:
This FABP1 gene encodes the fatty acid binding protein found in liver. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABP1 protein and FABP6 (the ileal fatty acid binding protein) are also able to bind bile acids. It is thought that FABPs roles include fatty acid uptake, transport, and metabolism. [provided by RefSeq, Mar 2011]
Wikipedia summary for L-FABP:
Fatty acid-binding protein 1 (FABP1) also known as liver-type fatty acid-binding protein (L-FABP) is a protein that in humans is encoded by the FABP1 gene.
Human L-FABP (FABP1) Protein General Information
| Protein names |
Liver-type fatty acid-binding protein, Short name=L-FABP |
| Sequence length |
127 AA. |
| Domain |
L-FABP forms a beta-barrel structure that accommodates hydrophobic ligands in its interior. |
| Sequence similarities: |
L-FABP belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. |
| Subcellular location: | Cytoplasm. |
General information above from UniProt
Function for L-FABP (FABP1) Protein
UniProtKB:
L-FABP binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm. L-FABP may be involved in intracellular lipid transport.
Genatlas:
- L-FABP is involved in intracellular lipid transport
- L-FABP has a significant role in oxidative stress
- L-FABP facilitates the cellular uptake, transport and metabolism of fatty acids and is also involved in the regulation of gene expressions and cell differentiation
- L-FABP modulates the function of peroxisomal lipid-metabolizing enzymes
