KLK3 / Kallikrein 3 Protein & Antibody

KLK3 / Kallikrein 3 Products

KLK3 / Kallikrein 3 Protein, Recombinant

Molecule	Species	Description //For Detailed Info. and Price------CLICK!	Cat. No
KLK3/Kallikrein 3	Human	KLK3 / Kallikrein 3 Protein, Recombinant	10771-H08H

KLK3 / Kallikrein 3 Antibody

Molecule	Application	Description //For Detailed Info. and Price------CLICK!	Cat. No
Human KLK3/Kallikrein 3	WB, ELISA	KLK3 / Kallikrein 3 Antibody	10771-RP01
Human KLK3/Kallikrein 3	WB, ELISA	KLK3 / Kallikrein 3 Antibody (Antigen Affinity Purified)	10771-RP02
Human KLK3/Kallikrein 3	ELISA	KLK3 / Kallikrein 3 Antibody	10771-R007

KLK3 / Kallikrein 3 cDNA Clone

Molecule	Species	Description //For Detailed Info. and Price------CLICK!	Cat. No
KLK3/Kallikrein 3	Human	KLK3 / Kallikrein 3 cDNA Clone / ORF Clone	HG10771-M

KLK3 / Kallikrein 3 Related Areas

Enzyme>>Protease & Regulator>>Serine Protease & Regulator>>Kallikrein>>KLK3/Kallikrein 3

Cancer>>Angiogenesis>>Kallikrein>>KLK3/Kallikrein 3

Cancer>>Cancer Biomarkers>>KLK3/Kallikrein 3

KLK3 / Kallikrein 3 Alternative Names

KLK3, Kallikrein 3, APS, KLK2A1, PSA, hK3 [Homo sapiens]

Klk3, Kallikrein 3, Klkb1, APS, Kal-3, Kal3, Klk3, PSA [Mus musculus]

KLK3 / Kallikrein 3 Related Products

Protein Products

Molecule	Species	Description //For Detailed Info. and Price------CLICK!
KLK1/KLK6/Kallikrein 1	Human	KLK1 / KLK6 / Kallikrein 1 Protein, Recombinant
KLK4/Kallikrein 4	Human	KLK4 / Kallikrein-4 Protein, Recombinant
KLK7/Kallikrein 7	Human	KLK7 / Kallikrein 7 Protein, Recombinant
KLK8/Kallikrein 8	Human	KLK8 / Kallikrein-8 Protein, Recombinant
KLK11/Kallikrein 11	Human	KLK11 / Kallikrein 11 Protein, Recombinant
KLK13/Kallikrein 13	Human	KLK13 / Kallikrein 13 Protein, Recombinant
KLK13/Kallikrein 13	Human	KLK13 / Kallikrein 13 Protein, Recombinant

Antibody Products

Molecule	Application	Description //For Detailed Info. and Price------CLICK!
Human KLK1/KLK6/Kallikrein 1	WB, ELISA	KLK1 / KLK6 / Kallikrein 1 Antibody, Rabbit PAb
Human KLK1/KLK6/Kallikrein 1	WB, ELISA	KLK1 / KLK6 / Kallikrein 1 Antibody, Rabbit PAb (Antigen Affinity Purified)
Human KLK7/Kallikrein 7	WB, ELISA	KLK7 / Kallikrein 7 Antibody, Rabbit PAb
Human KLK7/Kallikrein 7	WB, ELISA	KLK7 / Kallikrein 7 Antibody, Rabbit PAb (Antigen Affinity Purified)
Human KLK11/Kallikrein 11	WB, ELISA	KLK11 / Kallikrein 11 Rabbit MAb
Human KLK11/Kallikrein 11	WB, ELISA	KLK11 / Kallikrein 11 Rabbit PAb
Human KLK11/Kallikrein 11	WB, ELISA	KLK11 / Kallikrein 11 Rabbit PAb (Antigen Affinity Purified)
Human KLK13/Kallikrein 13	ELISA	KLK13 / Kallikrein 13 Mouse MAb
Human KLK13/Kallikrein 13	WB, ELISA	KLK13 / Kallikrein 13 Antibody, Rabbit PAb
Human KLK13/Kallikrein 13	WB, ELISA	KLK13 / Kallikrein 13 Antibody, Rabbit PAb (Antigen Affinity Purified)

cDNA Clone Products

Molecule	Species	Description //For Detailed Info. and Price------CLICK!
KLK1/KLK6/Kallikrein 1	Human	Homo sapiens KLK1 / KLK6 / Kallikrein 1 cDNA Clone(NM_002257.2)
KLK3/Kallikrein 3	Human	Homo sapiens KLK3 / Kallikrein 3 cDNA Clone(NM_001648.2)
KLK5/Kallikrein 5	Human	Homo sapiens KLK5 / Kallikrein 5 cDNA Clone(NM_012427.4)
KLK6/Kallikrein 6	Mouse	Mus musculus KLK6 / Kallikrein 6 cDNA Clone
KLK7/Kallikrein 7	Human	Homo sapiens KLK7 / Kallikrein 7 transcript variant 1 cDNA Clone
KLK8/Kallikrein 8	Mouse	Mouse KLK8 / Kallikrein-8 cDNA Clone / ORF Clone
KLK11/Kallikrein 11	Human	Homo sapiens KLK11 / Kallikrein 11 cDNA Clone(NM_006853.2)
KLK13/Kallikrein 13	Human	Homo sapiens KLK13 / Kallikrein 13 cDNA Clone(NM_015596.1)
KLKB1/Kallikrein B1	Human	Homo sapiens KLKB1 / Kallikrein B1 cDNA Clone(NM_000892.3)

KLK3 / Kallikrein 3 Background

KLK3, also known as Kallikrein 3, belongs to the peptidase S1 family, kallikrein subfamily. Kallikreins are a subgroup of serine proteases having diverse physiological functions. Many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. KLK3 contains 1 peptidase S1 domain. KLK3 is secreted by the epithelial cells of the prostate gland. KLK3 is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of KLK3, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. PSA is produced for the ejaculate where it liquifies the semen in the seminal coagulum and allows sperm to swim freely. KLK3 is also believed to be instrumental in dissolving the cervical mucous, allowing the entry of sperm. In those with prostate cancer, rising levels of PSA over time are associated with both localized and metastatic prostate cancer. Prostate test screening is controversial and may lead to unnecessary, even harmful, consequences in some patients.

KLK3 / Kallikrein 3 Related Studies

1. Koistinen H, et al. (2008) Development of peptides specifically modulating the activity of KLK2 and KLK3. Biol Chem. 389(6): 633-42.
2. Yousef GM, et al. (2002) Kallikreins, steroid hormones and ovarian cancer: is there a link? Minerva Endocrinol. 27(3): 157-66.
3. Parikh H, et al. (2011) Fine mapping the KLK3 locus on chromosome 19q13.33 associated with prostate cancer susceptibility and PSA levels. Hum Genet. 129(6): 675-85.