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KLK3 / Kallikrein 3 Protein & Antibody

KLK3 / Kallikrein 3 Products

KLK3 / Kallikrein 3 Protein, Recombinant

Molecule Species Description //For Detailed Info. and Price------CLICK! Cat. No
KLK3/Kallikrein 3 Human KLK3 / Kallikrein 3 Protein, Recombinant 10771-H08H

KLK3 / Kallikrein 3 Antibody

Molecule Application Description //For Detailed Info. and Price------CLICK! Cat. No
Human KLK3/Kallikrein 3 WB, ELISA KLK3 / Kallikrein 3 Antibody 10771-RP01
Human KLK3/Kallikrein 3 WB, ELISA KLK3 / Kallikrein 3 Antibody (Antigen Affinity Purified) 10771-RP02
Human KLK3/Kallikrein 3 ELISA KLK3 / Kallikrein 3 Antibody 10771-R007

KLK3 / Kallikrein 3 cDNA Clone

Molecule Species Description //For Detailed Info. and Price------CLICK! Cat. No
KLK3/Kallikrein 3 Human KLK3 / Kallikrein 3 cDNA Clone / ORF Clone HG10771-M

KLK3 / Kallikrein 3 Related Areas

Enzyme>>Protease & Regulator>>Serine Protease & Regulator>>Kallikrein>>KLK3/Kallikrein 3

Cancer>>Angiogenesis>>Kallikrein>>KLK3/Kallikrein 3

Cancer>>Cancer Biomarkers>>KLK3/Kallikrein 3

KLK3 / Kallikrein 3 Alternative Names

KLK3, Kallikrein 3, APS, KLK2A1, PSA, hK3 [Homo sapiens]

Klk3, Kallikrein 3, Klkb1, APS, Kal-3, Kal3, Klk3, PSA [Mus musculus]

KLK3 / Kallikrein 3 Related Products

Protein Products

Molecule Species Description //For Detailed Info. and Price------CLICK!
KLK1/KLK6/Kallikrein 1 Human KLK1 / KLK6 / Kallikrein 1 Protein, Recombinant
KLK4/Kallikrein 4 Human KLK4 / Kallikrein-4 Protein, Recombinant
KLK7/Kallikrein 7 Human KLK7 / Kallikrein 7 Protein, Recombinant
KLK8/Kallikrein 8 Human KLK8 / Kallikrein-8 Protein, Recombinant
KLK11/Kallikrein 11 Human KLK11 / Kallikrein 11 Protein, Recombinant
KLK13/Kallikrein 13 Human KLK13 / Kallikrein 13 Protein, Recombinant
KLK13/Kallikrein 13 Human KLK13 / Kallikrein 13 Protein, Recombinant

Antibody Products

Molecule Application Description //For Detailed Info. and Price------CLICK!
Human
KLK1/KLK6/Kallikrein 1
WB, ELISA KLK1 / KLK6 / Kallikrein 1 Antibody, Rabbit PAb
Human
KLK1/KLK6/Kallikrein 1
WB, ELISA KLK1 / KLK6 / Kallikrein 1 Antibody, Rabbit PAb (Antigen Affinity Purified)
Human
KLK7/Kallikrein 7
WB, ELISA KLK7 / Kallikrein 7 Antibody, Rabbit PAb
Human
KLK7/Kallikrein 7
WB, ELISA KLK7 / Kallikrein 7 Antibody, Rabbit PAb (Antigen Affinity Purified)
Human
KLK11/Kallikrein 11
WB, ELISA KLK11 / Kallikrein 11 Rabbit MAb
Human
KLK11/Kallikrein 11
WB, ELISA KLK11 / Kallikrein 11 Rabbit PAb
Human
KLK11/Kallikrein 11
WB, ELISA KLK11 / Kallikrein 11 Rabbit PAb (Antigen Affinity Purified)
Human
KLK13/Kallikrein 13
ELISA KLK13 / Kallikrein 13 Mouse MAb
Human
KLK13/Kallikrein 13
WB, ELISA KLK13 / Kallikrein 13 Antibody, Rabbit PAb
Human
KLK13/Kallikrein 13
WB, ELISA KLK13 / Kallikrein 13 Antibody, Rabbit PAb (Antigen Affinity Purified)

cDNA Clone Products

Molecule Species Description //For Detailed Info. and Price------CLICK!
KLK1/KLK6/Kallikrein 1 Human Homo sapiens KLK1 / KLK6 / Kallikrein 1 cDNA Clone(NM_002257.2)
KLK3/Kallikrein 3 Human Homo sapiens KLK3 / Kallikrein 3 cDNA Clone(NM_001648.2)
KLK5/Kallikrein 5 Human Homo sapiens KLK5 / Kallikrein 5 cDNA Clone(NM_012427.4)
KLK6/Kallikrein 6 Mouse Mus musculus KLK6 / Kallikrein 6 cDNA Clone
KLK7/Kallikrein 7 Human Homo sapiens KLK7 / Kallikrein 7 transcript variant 1 cDNA Clone
KLK8/Kallikrein 8 Mouse Mouse KLK8 / Kallikrein-8 cDNA Clone / ORF Clone
KLK11/Kallikrein 11 Human Homo sapiens KLK11 / Kallikrein 11 cDNA Clone(NM_006853.2)
KLK13/Kallikrein 13 Human Homo sapiens KLK13 / Kallikrein 13 cDNA Clone(NM_015596.1)
KLKB1/Kallikrein B1 Human Homo sapiens KLKB1 / Kallikrein B1 cDNA Clone(NM_000892.3)

KLK3 / Kallikrein 3 Background

KLK3, also known as Kallikrein 3, belongs to the peptidase S1 family, kallikrein subfamily. Kallikreins are a subgroup of serine proteases having diverse physiological functions. Many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. KLK3 contains 1 peptidase S1 domain. KLK3 is secreted by the epithelial cells of the prostate gland. KLK3 is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of KLK3, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. PSA is produced for the ejaculate where it liquifies the semen in the seminal coagulum and allows sperm to swim freely. KLK3 is also believed to be instrumental in dissolving the cervical mucous, allowing the entry of sperm. In those with prostate cancer, rising levels of PSA over time are associated with both localized and metastatic prostate cancer. Prostate test screening is controversial and may lead to unnecessary, even harmful, consequences in some patients.

KLK3 / Kallikrein 3 Related Studies

  1. Koistinen H, et al. (2008) Development of peptides specifically modulating the activity of KLK2 and KLK3. Biol Chem. 389(6): 633-42.
  2. Yousef GM, et al. (2002) Kallikreins, steroid hormones and ovarian cancer: is there a link? Minerva Endocrinol. 27(3): 157-66.
  3. Parikh H, et al. (2011) Fine mapping the KLK3 locus on chromosome 19q13.33 associated with prostate cancer susceptibility and PSA levels. Hum Genet. 129(6): 675-85.

 

KLK3 / Kallikrein 3 related areas, pathways, and other information

 

 

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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