Anti-Prostate Specific Antigen Antibody (Rabbit Polyclonal antibody) General Information
Anti-Prostate Specific Antigen Antibody
Reacts with: Human
Human Prostate Specific Antigen
Recombinant Human KLK3 / Kallikrein 3 protein (Catalog#10771-H08H)
Produced in rabbits immunized with purified, recombinant Human KLK3 / Kallikrein 3 (rh KLK3 / Kallikrein 3; Catalog#10771-H08H; P07288; Met 1-Pro 261). Total IgG was purified by Protein A affinity chromatography.
Polyclonal Rabbit IgG
0.2 μm filtered solution in PBS with 5% trehalose
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-Prostate Specific Antigen Antibody (Rabbit Polyclonal antibody) Validated Applications
**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********
Anti-Prostate Specific Antigen Antibody Alternative Names
Anti-APS Antibody;Anti-Hk3 Antibody;Anti-KLK2A1 Antibody;Anti-PSA Antibody
Prostate Specific Antigen Background Information
KLK3(Kallikrein 3), also known as Prostate Specific Antigen (PSA), kallikrein-related peptidase 3, Gamma-seminoprotein, is a secreted protein of the glandular kallikrein subfamily of serine proteases.KLK3 contains one peptidase S1 domain.KLK3 is a glycoprotein produced almost exclusively by the prostate gland. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers.
Immune Checkpoint Immunotherapy Cancer Immunotherapy Targeted Therapy
kallikrein related peptidase 3
Koistinen H, et al. (2008) Development of peptides specifically modulating the activity of KLK2 and KLK3. Biol Chem. 389(6): 633-42. Yousef GM, et al. (2002) Kallikreins, steroid hormones and ovarian cancer: is there a link? Minerva Endocrinol. 27(3): 157-66. Parikh H, et al. (2011) Fine mapping the KLK3 locus on chromosome 19q13.33 associated with prostate cancer susceptibility and PSA levels. Hum Genet. 129(6): 675-85.