- EGFR Signaling Pathway
- TGF-beta Signaling
- Canonical Wnt Signaling
- non-Canonical Wnt Signaling
- Notch Signaling
- p53 Pathway
- NF-kB Pathway
- Cytokine Signaling
|Catalog||Size (Price)||Quantity||In Stock||Operation|
KLK3 / Kallikrein 3 Antibody Datasheet
|Order or Inquire for KLK3 / Kallikrein 3 Antibody product||Quality antibodies||Antibody production services|
|Detection limit is 0.0195 ng/well in ELISA|
KLK3 / Kallikrein 3 Antibody Product Information
Recombinant Human KLK3 / Kallikrein 3 protein (Catalog#10771-H08H)
|Antibody Type :||Rabbit Monoclonal Antibody ( Rabbit mAb Service Platform )|
Clone ID :
|Ig Type :||
|Formulation :||0.2 μm filtered solution in PBS, 5% trehalose may be added in some batches. Please read the hardcopy of COA or contact our customer service to confirm the formulation.|
This antibody was obtained from a rabbit immunized with purified, recombinant Human KLK3 / Kallikrein 3 (rh KLK3 / Kallikrein 3; Catalog#10771-H08H; P07288; Met 1-Pro 261).
KLK3 / Kallikrein 3 Antibody Usage Guide
Human KLK3 / Kallikrein 3
|Direct ELISA :||This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Human KLK3. The detection limit for Human KLK3 is approximately 0.0195 ng/well.|
|Storage :||This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
KLK3 / Kallikrein 3 Antibody Related Products & Topics
|Molecule||Species||Description //For Detailed Info. and Price------CLICK!||Cat. No|
|KLK3/Kallikrein 3||Human||KLK3/Kallikrein 3 Protein, Recombinant||10771-H08H|
|Molecule||Application||Description //For Detailed Info. and Price------CLICK!||Cat. No|
|Human KLK3/Kallikrein 3||WB, ELISA||KLK3 / Kallikrein 3 Antibody||10771-RP01|
|Human KLK3/Kallikrein 3||WB, ELISA||KLK3 / Kallikrein 3 Antibody (Antigen Affinity Purified)||10771-RP02|
|Human KLK3/Kallikrein 3||ELISA||KLK3 / Kallikrein 3 Antibody||10771-R007|
KLK3 / Kallikrein 3 Antibody Background
Prostate-specific antigen, also known as Gamma-seminoprotein, Kallikrein-3, kallikrein-related peptidase 3, Semenogelase, KLK3 and PSA, is a secreted protein which belongs to thepeptidase S1 family and Kallikrein subfamily. KLK3/Kallikrein 3 contains one peptidase S1 domain. KLK3/Kallikrein 3 is a glycoprotein produced almost exclusively by the prostate gland. KLK3/Kallikrein 3 is produced for the ejaculate where it liquifies the semen in the seminal coagulum and allows sperm to swim freely.It is also believed to be instrumental in dissolving the cervical mucous, allowing the entry of sperm. Human KLK3/Kallikrein 3 and human KLK2 are closely related products of the human kallikrein genes KLK3 and KLK2, respectively. Both KLK3/Kallikrein 3 and human kallikrein 2 are produced and secreted in the prostate and have important applications in the diagnosis of prostate cancer. Understanding the mechanism by which genetic variation in KLK3/Kallikrein 3 affects prostate cancer risk has important implications for study of the biological role of KLK3/Kallikrein 3 in prostate tumorigenesis.
- Koistinen,H. et al., 2008, Biol Chem. 389 (6): 633-42.
- David,A. et al.,2002, J Biol Chem. 277 (20): 18084-90.
- Andriole GL, et al., 2009, New Eng. J. Med. 360 (13): 1310.
- Schroder FH, et al., 2009, New Eng. J. Med. 360 (13): 1320.