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KLK13 / Kallikrein-13 Antibody, Rabbit PAb, Antigen Affinity Purified

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    Human KLK-13 Antibody Product Information
    Immunogen:Recombinant Human KLK13 protein (Catalog#10199-H08H)
    Clone ID:
    Ig Type:Rabbit IgG
    Concentration:
    Formulation:0.2 μm filtered solution in PBS with 5% trehalose
    Preparation:Produced in rabbits immunized with purified, recombinant Human KLK13 / Kallikrein13 (rh KLK13; Catalog#10199-H08H; NP_056411.1; Met 1-Ile 262). KLK13 specific IgG was purified by human KLK13 affinity chromatography .
    Other KLK-13 Antibody Products
    KLK13/Kallikrein 13 Background

    Tissue kallikrein 13 (hK13), also known as KLK-L4 (kallikrein-like gene 4), is a member of the human tissue kallikrein family of serine proteases having diverse physiological functions in many tissues. The KLK13 gene resides on chromosome 19q13.3-4 along with other 14 members in a gene cluster and shares a high degree of homology. KLK13 is a trypsin-like, secreted serine protease expressed specifically in the testicular tissue including prostate, salivary gland, breast, and testis. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and may play a role in metastasis. KLK13 may be involved in the pathogenesis and/or progression of breast and ovary cancers, and is regarded as a novel cancer biomarker. In addition, KLK13 interacts and forms complexes with several serum protease inhibitors, such as alpha2-macroglobulin, and its expression is regulated by steroid hormones.

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