All KIR3DL1 reagents are produced in house and quality controlled, including 2 KIR3DL1 Antibody, 13 KIR3DL1 Gene, 1 KIR3DL1 qPCR. All KIR3DL1 reagents are ready to use.
KIR3DL1 antibodies are validated with different applications, which are WB, IHC-P.
KIR3DL1 cDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each KIR3DL1 of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.
KIR3DL1 is a natural killer (NK) cell receptor that recognizes the Bw4 epitope of human leukocyte antigen (HLA) class I molecules. KIR3DL1 is a polymorphic inhibitory receptor that modulates NK cell activity through interacting with HLA-A and HLA-B alleles that carry the Bw4 epitope. Amino acid polymorphisms throughout KIR3DL1 impact receptor surface expression and affinity for HLA. Genetic studies suggest that KIR3DL1 variation has functional significance in several disease states, including HIV infection.KIR3DL1 is a highly polymorphic inhibitory killer cell Ig-like receptor (KIR) implicated in resistance to viral diseases such as AIDS. KIR3DL1 contains three Ig domains and is specific for MHC class I (MHC-I) molecules belonging to the HLA-Bw4 serogroup. The receptor's second and third Ig domains confer the Bw4 specificity.