Anti-KIR2DL3 Antibody (Rabbit Polyclonal antibody) General Information
Reacts with: Human
Recombinant Human KIR2DL3 protein (Catalog#12828-H08H)
Produced in rabbits immunized with purified, recombinant Human KIR2DL3 (rh KIR2DL3; Catalog#12828-H08H; AAX23102.1; Met 1-His 245). KIR2DL3 specific IgG was purified by Human KIR2DL3 affinity chromatography.
Polyclonal Rabbit IgG
Protein A & Antigen Affinity
0.2 μm filtered solution in PBS with 5% trehalose
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-KIR2DL3 Antibody (Rabbit Polyclonal antibody) Validated Applications
**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********
Anti-KIR2DL3 Antibody Alternative Names
Anti-CD158b Antibody;Anti-CD158B2 Antibody;Anti-CU464054.1 Antibody;Anti-GL183 Antibody;Anti-KIR-023GB Antibody;Anti-KIR-K7b Antibody;Anti-KIR-K7c Antibody;Anti-KIR2DS5 Antibody;Anti-KIRCL23 Antibody;Anti-MGC129943 Antibody;Anti-NKAT Antibody;Anti-NKAT2 Antibody;Anti-NKAT2A Antibody;Anti-NKAT2B Antibody;Anti-p58 Antibody
KIR2DL3 Background Information
Killer cell immunoglobulin-like receptor 2DL3, also known as CD158 antigen-like family member B2, KIR-023GB, Killer inhibitory receptor cl 2-3, MHC class I NK cell receptor, NKAT2a, NKAT2b, Natural killer-associated transcript 2, p58 natural killer cell receptor clone CL-6, p58.2 MHC class-I-specific NK receptor, CD158b2 and KIR2DL3, is a single-pass type I membrane protein which belongs to the immunoglobulin superfamily. KIR2DL3 contains 2 Ig-like C2-type (immunoglobulin-like) domains. KIR2DL3 interacts with ARRB2. KIR2DL3 is a receptor on natural killer (NK) cells for HLA-C alleles (HLA-Cw1, HLA-Cw3 and HLA-Cw7). KIR2DL3 inhibits the activity of NK cells thus preventing cell lysis.
killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 3
Selvakumar A., et al., 1997, Immunol. Rev. 155:183-196. Wilson M.J., et al., 1997, Tissue Antigens 49:574-579. Maenaka K., et al., 1999, Structure 7:391-398. Vitale,M. et al., 2004, Int Immunol. 16 (10):1459-66. Yu M.-C., et al., 2008, Nat. Immunol. 9:898-907.