JNK1 cDNA ORF Clone in Cloning Vector, Human

Cat: HG10795-M
Contact us:
215-583-7898
order@sinobiological.com
Distributors
All JNK1 Reagents
CRO Services
Product recommended

All JNK1 Reagents
JNK1 cDNA ORF Clone in Cloning Vector, Human General Information
Gene
Species
Human
NCBI Ref Seq
RefSeq ORF Size
1284 bp
Sequence Description
Identical with the Gene Bank Ref. ID sequence.
Description
Full length Clone DNA of Human mitogen-activated protein kinase 8, transcript variant JNK1-b2.
Plasmid
Vector
pMD18-T Simple Vector
Sequencing Primers
M13-47 and RV-M
Quality Control
The plasmid is confirmed by full-length sequencing.
Screening
Antibiotic in E.coli
Ampicillin
Storage & Shipping
Shipping
Each tube contains lyophilized plasmid.
Storage
The lyophilized plasmid can be stored at ambient temperature for three months.
JNK1 cDNA ORF Neucleotide Sequence and Amino Acid Sequence Information

**Sino Biological guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories.**

JNK1 cDNA ORF Clone in Cloning Vector, Human Alternative Names
JNK cDNA ORF Clone, Human;JNK-46 cDNA ORF Clone, Human;JNK1 cDNA ORF Clone, Human;JNK1A2 cDNA ORF Clone, Human;JNK21B1/2 cDNA ORF Clone, Human;PRKM8 cDNA ORF Clone, Human;SAPK1 cDNA ORF Clone, Human;SAPK1c cDNA ORF Clone, Human
JNK1 Background Information

Mitogen-activated protein kinase 8 (MAPK8), also known as JNK1, is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The protein kinases JNK1 has been found to serve as critical molecular links between obesity, metabolic inflammation, and disorders of glucose homeostasis. It is critically involved in the promotion of diet-induced obesity, metabolic inflammation and beta-cell dysfunction. The selective deficiency of JNK1 in the murine nervous system is sufficient to suppress diet-induced obesity. Genetic analysis indicates that the effects of JNK1 can be separated from effects of JNK1 on obesity. JNK1 is a potential pharmacological target for the development of drugs that might be useful for the treatment of metabolic syndrome, and type 2 diabetes. Furthermore, JNK1 plays a major role in the hypoxic cellular damage. JNK1 protein might be an attractive target for antihypoxic therapy in increasing resistance to many pathological conditions and diseases, leading to the oxygen deficit.

Full Name
mitogen-activated protein kinase 8
Research Areas
References
  • Betigeri S, et al. (2006) JNK1 as a molecular target to limit cellular mortality under hypoxia. Mol Pharm. 3(4): 424-30.
  • Solinas G, et al. (2010) JNK1 and IKKbeta: molecular links between obesity and metabolic dysfunction. FASEB J. 24(8): 2596-611.
  • Sabio G, et al. (2010) Role of the hypothalamic-pituitary-thyroid axis in metabolic regulation by JNK1. Genes Dev. 24(3): 256-64.
  • JNK1 cDNA ORF Clone, Mouse, Related Products

    Product Name Catalog#(PDF)
    JNK1 cDNA ORF Clone in Cloning Vector, Mouse MG50009-M
    JNK1 cDNA ORF Clone, Mouse, untagged MG50009-UT
    JNK1 Lentiviral cDNA ORF Clone, Mouse, C-GFPSpark® tag MG50009-ACGLN
    JNK1 cDNA ORF Clone, Mouse, C-GFPSpark® tag MG50009-ACG
    JNK1 cDNA ORF Clone, Mouse, N-GFPSpark® tag MG50009-ANG
    JNK1 cDNA ORF Clone, Mouse, C-OFPSpark® tag MG50009-ACR
    JNK1 cDNA ORF Clone, Mouse, N-OFPSpark® tag MG50009-ANR
    JNK1 cDNA ORF Clone, Mouse, C-DDK (Flag®) tag MG50009-CF
    JNK1 cDNA ORF Clone, Mouse, N-DDK (Flag®) tag MG50009-NF
    JNK1 cDNA ORF Clone, Mouse, C-His tag MG50009-CH
    JNK1 cDNA ORF Clone, Mouse, N-His tag MG50009-NH
    JNK1 cDNA ORF Clone, Mouse, C-HA tag MG50009-CY
    JNK1 cDNA ORF Clone, Mouse, N-HA tag MG50009-NY
    JNK1 cDNA ORF Clone, Mouse, C-Myc tag MG50009-CM
    JNK1 cDNA ORF Clone, Mouse, N-Myc tag MG50009-NM
    JNK1 qPCR Primer Pairs, Mouse MP200009

    JNK1 cDNA ORF Clone, Human, Related Products

    Product Name Catalog#(PDF)
    JNK1 cDNA ORF Clone, Human, untagged HG10795-UT
    JNK1 Lentiviral cDNA ORF Clone, Human, C-GFPSpark® tag HG10795-ACGLN
    JNK1 cDNA ORF Clone, Human, C-GFPSpark® tag HG10795-ACG
    JNK1 cDNA ORF Clone, Human, N-GFPSpark® tag HG10795-ANG
    JNK1 cDNA ORF Clone, Human, C-OFPSpark® tag HG10795-ACR
    JNK1 cDNA ORF Clone, Human, N-OFPSpark® tag HG10795-ANR
    JNK1 cDNA ORF Clone, Human, C-DDK (Flag®) tag HG10795-CF
    JNK1 cDNA ORF Clone, Human, N-DDK (Flag®) tag HG10795-NF
    JNK1 cDNA ORF Clone, Human, C-His tag HG10795-CH
    JNK1 cDNA ORF Clone, Human, N-His tag HG10795-NH
    JNK1 cDNA ORF Clone, Human, C-HA tag HG10795-CY
    JNK1 cDNA ORF Clone, Human, N-HA tag HG10795-NY
    JNK1 cDNA ORF Clone, Human, C-Myc tag HG10795-CM
    JNK1 cDNA ORF Clone, Human, N-Myc tag HG10795-NM
    JNK1 qPCR Primer Pairs, Human HP100709
    info info
    添加购物车成功! 添加购物车失败!