|ELISA(Det)||1:1000-1:10000||This antibody will detect Human Junctional Adhesion Molecule A in ELISA pair set (Catalog: # SEKA10198). In a sandwich ELISA, it can be used as detection antibody when paired with (Catalog: # 10198-MM08).|
**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********
Junctional adhesion molecule-A (JAM-A), also known as F11 receptor (F11R) or Cluster of Differentiation 321 (CD321), is a transmembrane protein expressed at tight junctions of epithelial and endothelial cells, as well as on circulating leukocytes. JAM-A protein serves as a serotype-independent receptor for mammalian orthoreoviruses (reoviruses). It is also a ligand for the integrin LFA1, involves in leukocyte transmigration. As a cell adhesion molecule of the immunoglobulin superfamily, JAM-A protein involves in platelet adhesion, secretion and aggregation, and plays a crucial role in inflammatory thrombosis and atherosclerosis. In addition, it may be a potential therapeutic target for breast cancer.
|Product Description||Host||Clonality||Application||Catalog# (PDF)|
|Anti-JAM-A Antibody (PE)||Mouse||Monoclonal||FCM||10198-MM04-P|
|Anti-JAM-A Antibody (APC)||Mouse||Monoclonal||FCM||10198-MM04-A|
|Anti-JAM-A Antibody (FITC)||Mouse||Monoclonal||FCM||10198-MM04-F|