Influenza Neuraminidase / Influenza NA Proteins

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Influenza Neuraminidase (NA) Background

Neuraminidase is a single-pass type II membrane protein which exists as a homotetramer. It specifically catalyzes the hydrolysis removal of terminal sialic acid residues, and thus also called sialidase. Influenza neuraminidase promotes influenza virus release from infected cells and facilitates virus spread within the respiratory tract. At present, there are only three licensed anti-Influenza drugs namely Relenza (Zanamivir - ZMV), Tamiflu (Oseltamivir - OTV) and Amantadine/Rimantadine. The latter targets the M2 ion channel whereas the other compounds target neuraminidase and were designed through structure-based enzyme inhibitor programmes. The neuraminidase inhibitors interfere with the release of progeny influenza virus from infected host cells, thereby halts the spread of infection in the respiratory tract. The neuraminidase inhibitors are effective against all neuraminidase subtypes and, therefore, against all strains of influenza, a key point in epidemic and pandemic preparedness. In addition, The neuraminidase inhibitors are associated with very little toxicity and are far less likely to promote the development of drug-resistant influenza. Because of a broader antiviral spectrum, better tolerance, and less potential for emergence of resistance than is seen with the M2 inhibitors, the neuraminidase inhibitors represent an important advance in the treatment of influenza.

Influenza Neuraminidase (NA) Protein Products

Influenza Neuraminidase (NA) Protein: H1N1, A/California/04/2009

Product (CLICK for detailed Info. and price)	Species	Molecule	Description	Cat. No
Influenza Neuraminidase (NA) Protein H1N1, A/California/04/2009	Influenza A H1N1 Virus	NA	Fc Tag	11058-V01H
Influenza Neuraminidase (NA) Protein H1N1, A/California/04/2009	Influenza A H1N1 Virus	NA	His Tag	11058-V07H
Influenza Neuraminidase (NA) Protein H1N1, A/California/04/2009	Influenza A H1N1 Virus	NA	His Tag	11058-V07B
Influenza Neuraminidase (NA) Protein H1N1, A/California/04/2009	Influenza A H1N1 Virus	NA	Native	11058-VNAHC
Influenza Neuraminidase (NA) Protein H1N1, A/California/04/2009	Influenza A H1N1 Virus	NA	Native	11058-VNAHC1
Influenza Neuraminidase (NA) Protein H1N1, A/California/04/2009	Influenza A H1N1 Virus	NA	His Tag	11058-V07HC

Influenza Neuraminidase (NA) Protein: H3N2, A/Babol/36/2005

Product (CLICK for detailed Info. and price)	Species	Molecule	Description	Cat. No
Influenza Neuraminidase (NA) Protein H3N2, A/Babol/36/2005	Influenza A H3N2 Virus	NA	His Tag	40017-V07H
Influenza Neuraminidase (NA) Protein H3N2, A/Babol/36/2005	Influenza A H3N2 Virus	NA	Native	40017-VNAHC1
Influenza Neuraminidase (NA) Protein H3N2, A/Babol/36/2005	Influenza A H3N2 Virus	NA	Native	40017-VNAHC2
Influenza Neuraminidase (NA) Protein H3N2, A/Babol/36/2005	Influenza A H3N2 Virus	NA	Native	40017-VNAHC3
Influenza Neuraminidase (NA) Protein H3N2, A/Babol/36/2005	Influenza A H3N2 Virus	NA	Native	40017-VNAHC4
Influenza Neuraminidase (NA) Protein H3N2, A/Babol/36/2005	Influenza A H3N2 Virus	NA	Native	40017-VNAHC

Influenza Neuraminidase (NA) Protein: H5N1, A/Anhui/1/2005

Product (CLICK for detailed Info. and price)	Species	Molecule	Description	Cat. No
Influenza Neuraminidase (NA) Protein H5N1, A/Anhui/1/2005	Influenza A H5N1 Virus	NA	Native	11676-VNAHC
Influenza Neuraminidase (NA) Protein H5N1, A/Anhui/1/2005	Influenza A H5N1 Virus	NA	Native	11676-VNAHC1

Influenza Neuraminidase (NA) Protein: H5N1, A/Hubei/2011

Product (CLICK for detailed Info. and price)	Species	Molecule	Description	Cat. No
Influenza Neuraminidase (NA) Protein H5N1, A/Hubei/2011	Influenza A H5N1 Virus	NA	His Tag	40018-V07H

Influenza Neuraminidase (NA) Protein: H9N2, A/Chicken/Hong Kong/G9/97

Product (CLICK for detailed Info. and price)	Species	Molecule	Description	Cat. No
Influenza Neuraminidase (NA) Protein H9N2, A/Chicken/Hong Kong/G9/97	Influenza A H9N2 Virus	NA	Native	40034-VNAHC

Influenza Neuraminidase (NA) cDNA Clone Products

Influenza Neuraminidase (NA) cDNA clone: H9N2, A/Chicken/Hong Kong/G9/97

Product (CLICK for detailed Info. and price)	Species	Molecule	Description	Cat. No
Influenza Neuraminidase (NA) cDNA clone H9N2, A/Chicken/Hong Kong/G9/97	Influenza A H9N2 Virus	NA		VG40034-G

Influenza Neuraminidase (NA) cDNA clone: H9N2, A/Hong Kong/1073/99

Product (CLICK for detailed Info. and price)	Species	Molecule	Description	Cat. No
Influenza Neuraminidase (NA) cDNA clone H9N2, A/Hong Kong/1073/99	Influenza A H9N2 Virus	NA	Codon Optimized	VG40040-G

Browse Additional Influenza Neuraminidase (NA) & Antibody by Subtype

H1N1 Neuraminidase

H3N2 Neuraminidase

H5N1 Neuraminidase

H9N2 Neuraminidase

Additional Influenza Research Reagents

Influenza Antibodies

Influenza ELISA Kit

Influenza Hemagglutinin (HA) Protein & Antibody

Influenza Neuraminidase (NA) Protein & Antibody

Influenza Nucleoprotein (NP) & Antibody

Influenza M1 Protein

Influenza NS1 Protein

Influenza NS2 Protein (NEP)

Additional Neuraminidase Products

Clostridium Perfringens Neuraminidase (NA)

Micromonospora viridifaciens Neuraminidase (NA)