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Influenza Neuraminidase / Influenza NA Proteins        H7N9 Protein & Antibody   New !

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Influenza Neuraminidase (NA) Background

Neuraminidase is a single-pass type II membrane protein which exists as a homotetramer. It specifically catalyzes the hydrolysis removal of terminal sialic acid residues, and thus also called sialidase. Influenza neuraminidase (NA) promotes influenza virus release from infected cells and facilitates virus spread within the respiratory tract. At present, there are only three licensed anti-Influenza drugs namely Relenza (Zanamivir - ZMV), Tamiflu (Oseltamivir - OTV) and Amantadine/Rimantadine. The latter targets the M2 ion channel whereas the other compounds target neuraminidase and were designed through structure-based enzyme inhibitor programmes. The neuraminidase inhibitors interfere with the release of progeny influenza virus from infected host cells, thereby halts the spread of infection in the respiratory tract. The neuraminidase inhibitors are effective against all neuraminidase subtypes and, therefore, against all strains of influenza, a key point in epidemic and pandemic preparedness. In addition, The neuraminidase inhibitors are associated with very little toxicity and are far less likely to promote the development of drug-resistant influenza. Because of a broader antiviral spectrum, better tolerance, and less potential for emergence of resistance than is seen with the M2 inhibitors, the neuraminidase inhibitors represent an important advance in the treatment of influenza.

The viral neuraminidases are frequently used as an antigenic determinants found on the surface of the Influenza virus. Some variants of the influenza neuraminidase (NA) confer more virulence to the virus than others. Swiss-Prot lists 137 types of neuraminidase from various species as of October 18, 2006, while nine subtypes of influenza neuraminidase (NA) are known. Influenza neuraminidase (NA) exists as a mushroom-shape projection on the surface of the influenza virus. It has a head consisting of four co-planar and roughly spherical subunits, and a hydrophobic region that is embedded within the interior of the virus' membrane.

Influenza Neuraminidase (NA) Protein Products

Influenza Neuraminidase (NA) Protein: H7N9

Product (CLICK for detailed Info. and price) Species Molecule Tag Cat. No
Influenza Neuraminidase (NA) Protein
H7N9, A/Anhui/1/2013
Influenza A H7N9 Virus NA - 40108-VNAHC
Influenza Neuraminidase (NA) Protein
H7N9, A/Shanghai/1/2013
Influenza A H7N9 Virus NA - 40109-VNAHC
Influenza Neuraminidase (NA) Protein
H7N9, A/Anhui/1/2013
Influenza A H7N9 Virus NA His Tag 40108-V07H

Influenza Neuraminidase (NA) Protein: H1N1, A/California/04/2009

Product (CLICK for detailed Info. and price) Species Molecule Tag Cat. No
Influenza Neuraminidase (NA) Protein
H1N1 ( N295S mutation ) , A/California/04/2009
Influenza A H1N1 Virus NA - 11058-VNAHC2
Influenza Neuraminidase (NA) Protein
H1N1, A/California/04/2009
Influenza A H1N1 Virus NA Fc Tag 11058-V01H
Influenza Neuraminidase (NA) Protein
H1N1, A/California/04/2009
Influenza A H1N1 Virus NA His Tag 11058-V07H
Influenza Neuraminidase (NA) Protein
H1N1, A/California/04/2009
Influenza A H1N1 Virus NA His Tag 11058-V07B
Influenza Neuraminidase (NA) Protein
H1N1, A/California/04/2009
Influenza A H1N1 Virus NA - 11058-VNAHC
Influenza Neuraminidase (NA) Protein (H274Y)
H1N1, A/California/04/2009
Influenza A H1N1 Virus NA - 11058-VNAHC1
Influenza Neuraminidase (NA) Protein
H1N1, A/California/04/2009
Influenza A H1N1 Virus NA His Tag 11058-V07HC

Influenza Neuraminidase (NA) Protein: H3N2, A/Babol/36/2005

Product (CLICK for detailed Info. and price) Species Molecule Tag Cat. No
Influenza Neuraminidase (NA) Protein
H3N2, A/Babol/36/2005
Influenza A H3N2 Virus NA His Tag 40017-V07H
Influenza Neuraminidase (NA) Protein (E119V)
H3N2, A/Babol/36/2005
Influenza A H3N2 Virus NA - 40017-VNAHC1
Influenza Neuraminidase (NA) Protein (N294S)
H3N2, A/Babol/36/2005
Influenza A H3N2 Virus NA - 40017-VNAHC2
Influenza Neuraminidase (NA) Protein (R292K)
H3N2, A/Babol/36/2005
Influenza A H3N2 Virus NA - 40017-VNAHC3
Influenza Neuraminidase (NA) Protein (H274Y)
H3N2, A/Babol/36/2005
Influenza A H3N2 Virus NA - 40017-VNAHC4
Influenza Neuraminidase (NA) Protein
H3N2, A/Babol/36/2005
Influenza A H3N2 Virus NA - 40017-VNAHC

Influenza Neuraminidase (NA) Protein: H5N1, A/Anhui/1/2005

Product (CLICK for detailed Info. and price) Species Molecule Tag Cat. No
Influenza Neuraminidase (NA) Protein
H5N1, A/Anhui/1/2005
Influenza A H5N1 Virus NA - 11676-VNAHC
Influenza Neuraminidase (NA) Protein (H274Y)
H5N1, A/Anhui/1/2005
Influenza A H5N1 Virus NA - 11676-VNAHC1

Influenza Neuraminidase (NA) Protein: H5N1, A/Hubei/2011

Product (CLICK for detailed Info. and price) Species Molecule Tag Cat. No
Influenza Neuraminidase (NA) Protein
H5N1, A/Hubei/2011
Influenza A H5N1 Virus NA His Tag 40018-V07H

Influenza Neuraminidase (NA) Protein: H9N2, A/Chicken/Hong Kong/G9/97

Product (CLICK for detailed Info. and price) Species Molecule Tag Cat. No
Influenza Neuraminidase (NA) Protein
H9N2, A/Chicken/Hong Kong/G9/97
Influenza A H9N2 Virus NA - 40034-VNAHC

Influenza Neuraminidase (NA) cDNA Clone Products

Influenza Neuraminidase (NA) cDNA clone: H9N2, A/Chicken/Hong Kong/G9/97

Product (CLICK for detailed Info. and price) Species Molecule Tag Cat. No
Influenza Neuraminidase (NA) cDNA clone
H9N2, A/Chicken/Hong Kong/G9/97
Influenza A H9N2 Virus NA   VG40034-G

Influenza Neuraminidase (NA) cDNA clone: H9N2, A/Hong Kong/1073/99

Product (CLICK for detailed Info. and price) Species Molecule Tag Cat. No
Influenza Neuraminidase (NA) cDNA clone
H9N2, A/Hong Kong/1073/99
Influenza A H9N2 Virus NA Codon Optimized VG40040-G

Browse Additional Influenza Neuraminidase (NA) & Antibody by Subtype

H1N1 Neuraminidase

H3N2 Neuraminidase

H5N1 Neuraminidase

H9N2 Neuraminidase

H7N9 Neuraminidase NEW!

     

Additional Influenza Research Reagents

Additional Neuraminidase Products

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Pandemic Influenza Hemagglutinin (HA) / Neuraminidase (NA) & Antibodies

Influenza Hemagglutinin (HA) Protein

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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