Influenza B HA / Hemagglutinin Antibody

Influenza B Virus HA / Hemagglutinin Antibody

Influenza B HA / Hemagglutinin Antibody Product Information

• Immunogen: Recombinant Influenza B virus HA protein ( Catalog#11053-V08H )
• Antibody Type: Rabbit Polyclonal Antibody ( Antibody Purification Platform )
• Ig Type: Rabbit IgG
• Formulation: 0.2 μm filtered solution in PBS with 5% trehalose
• Preparation: Produced in rabbits immunized with purified, human cell-derived, recombinant Influenza B virus HA ( rv HA ; Catalog#11053-V08H ; ACA33493.1 ; Met 1 - Ala 555 ). Total IgG was purified by Protein A affinity chromatography.

Influenza B HA / Hemagglutinin Antibody Usage Guide

• Specificity: Influenza B ( B/Florida/04/06 ) HA
• Direct ELISA: This antibody can be used at 0.5 - 1.0 μg/mL with the appropriate secondary reagents to detect Influenza B virus HA. The detection limit for Influenza B virus HA is 0.00245 ng/well
• Storage: This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃. Preservative-Free.
  Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

Related Influenza Virus Research Tools

• Influenza Virus Research Tools
• Influenza Hemagglutinin & Antibody
• Influenza Antibody
• Influenza B Hemagglutinin & Antibody
• B/Florida/04/06

Influenza B HA / Hemagglutinin Antibody Background

Influenza (flu) is a respiratory infection in mammals and birds. This virus is divided into three main types (A, B and C). Influenza A is found in a wide variety of bird and mammal species. Influenza B is largely confined to humans and is an important cause of morbidity. Influenza C infects humans, dogs and pigs, sometimes causing both severe illness and local epidemics. Influenza A is further divided into subtypes based on differences in the membrane proteins hemagglutinin (HA) and neuraminidase (NA). The notation HhNn is used to refer to the subtype comprising the hth discovered HA protein and the nth discovered NA protein. The HA is a trimer with a receptor binding pocket on the globular head of each monomer. Subtypes are further divided into strains. Each genetically distinct virus isolate is usually considered to be a separate strain. Influenza B viruses are only known to infect humans and seals, giving them influenza. This limited host range is apparently responsible for the lack of Influenza virus B caused influenza pandemics in contrast with those caused by the morphologically similar Influenza virus A as both mutate by both genetic drift and reassortment. Influenza B viruses evolve slower than A viruses and faster than C viruses. Influenza B virus mutates at a rate 2 to 3 times lower than type A. However, influenza B mutates enough that lasting immunity is not possible.

References

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