IgG1 (Protein|Antibody|cDNA Clone|ELISA Kit)

All IgG1 reagents are produced in house and quality controlled, including 1 IgG1 Antibody, 1 IgG1 Lysate, 3 IgG1 Protein. All IgG1 reagents are ready to use.

Recombinant IgG1 proteins are expressed by CHO Cells, HEK293 Cells with fusion tags as Native.

IgG1antibodies are validated with different applications, which are ELISA.

IgG1 Protein (3)

Species

IgG1 Protein, Human, Recombinant (103 Cys/Ser)

10702-HNAH

Expression host: HEK293 Cells

Human IgG1/IgG1 Fc Protein 9047

IgG1 Protein, Human, Recombinant (103 Cys/Ser)

10702-HNAC

Expression host: CHO Cells

Human IgG1/IgG1 Fc Protein 9046

IgG1 Protein, Mouse, Recombinant (102 Cys/Ser)

10690-MNAH

Expression host: HEK293 Cells

Mouse IgG1/IgG1 Fc Protein 9023
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IgG1 Antibody (1)

Application
Clonality
Host

IgG1 / IgG1 Fc Antibody, Rabbit PAb

10702-RP01

Application: ELISA

Clonality: PAb

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IgG1 Lysate (1)

As a monomeric immunoglobulin that is predominately involved in the secondary antibody response and the only isotype that can pass through the human placenta, Immunoglobulin G (IgG) is synthesized and secreted by plasma B cells, and constitutes 75% of serum immunoglobulins in humans. IgG antibodies protect the body against the pathogens by agglutination and immobilization, complement activation, toxin neutralization, as well as the antibody-dependent cell-mediated cytotoxicity (ADCC). IgG tetramer contains two heavy chains (50 kDa ) and two light chains (25 kDa) linked by disulfide bonds, that is the two identical halves form the Y-like shape. IgG is digested by pepsin proteolysis into Fab fragment (antigen-binding fragment) and Fc fragment ("crystallizable" fragment). IgG1 is most abundant in serum among the four IgG subclasses (IgG1, 2, 3 and 4) and binds to Fc receptors (FcγR ) on phagocytic cells with high affinity. Fc fragment is demonstrated to mediate phagocytosis, trigger inflammation, and target Ig to particular tissues. Protein G or Protein A on the surface of certain Staphylococcal and Streptococcal strains specifically binds with the Fc region of IgGs, and has numerous applications in biotechnology as a reagent for affinity purification. Recombinant IgG Fc Region is suggested to represent a potential anti-inflammatory drug for treatment of human autoimmune diseases.

Protein
Antibody
Lysate
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