All CD51 & ITGB6 Heterodimer reagents are produced in house and quality controlled, including 2 CD51 & ITGB6 Heterodimer Antibody, 2 CD51 & ITGB6 Heterodimer Lysate, 2 CD51 & ITGB6 Heterodimer Protein. All CD51 & ITGB6 Heterodimer reagents are ready to use.
Recombinant CD51 & ITGB6 Heterodimer proteins are expressed by HEK293 Cells with fusion tags as C-Flag & C-His.
CD51 & ITGB6 Heterodimerantibodies are validated with different applications, which are ELISA.
Integrin alpha-5, also known as ITGA5, is a single-pass type I membrane protein which belongs to the integrin alpha chain family. ITGA5 contains 7 FG-GAP repeats. Alpha chain 5 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form a fibronectin receptor. ITGAV&ITGB6 is a receptor for fibronectin and cytotactin. It recognizes the sequence R-G-D in its ligands. Internalisation of ITGAV&ITGB6 via clathrin-mediated endocytosis promotes carcinoma cell invasion.