Quick Order

Text Size:AAA

IL6 / Interleukin-6 Antibody, Rabbit PAb, Antigen Affinity Purified

DatasheetReviewsRelated ProductsProtocols
Cynomolgus IL6 Antibody Product Information
Immunogen:Recombinant Cynomolgus IL6 / Interleukin-6 protein (Catalog#90197-CNAE)
Clone ID:
Ig Type:Rabbit IgG
Concentration:
Endotoxin:
Formulation:0.2 μm filtered solution in PBS with 5% trehalose
Preparation:Produced in rabbits immunized with purified, recombinant Cynomolgus IL6 / Interleukin-6 (Catalog#90197-CNAE; Pro29-Met212). IL6 / Interleukin-6 specific IgG was purified by Cynomolgus IL6 / Interleukin-6 affinity chromatography.
Cynomolgus IL6 Antibody Usage Guide
Specificity:Cynomolgus IL6 / Interleukin-6
Application:ELISA, IHC-P

ELISA: 0.1-0.2 μg/mL

This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Cynomolgus IL6 / Interleukin-6. The detection limit for Cynomolgus IL6 / Interleukin-6 is approximately < 0.039 ng/well.

IHC-P: 0.1-1 μg/mL

Storage:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Cynomolgus IL6 Antibody IHC Application Image
IL6 / Interleukin-6 Antibody, Rabbit PAb, Antigen Affinity Purified, Immunohistochemistry
[Click to enlarge image]
Caption:
Immunochemical staining of cynomolgus IL6 in human liver with rabbit polyclonal antibody (0.5 µg/mL, formalin-fixed paraffin embedded sections).
IL6 / Interleukin-6 Antibody, Rabbit PAb, Antigen Affinity Purified, Immunohistochemistry
[Click to enlarge image]
Caption:
Immunochemical staining of cynomolgus IL6 in human spleen with rabbit polyclonal antibody (0.5 µg/mL, formalin-fixed paraffin embedded sections).
IL6 / Interleukin-6 Antibody, Rabbit PAb, Antigen Affinity Purified, Immunohistochemistry
[Click to enlarge image]
Caption:
Immunochemical staining of cynomolgus IL6 in human tonsil with rabbit polyclonal antibody (0.5 µg/mL, formalin-fixed paraffin embedded sections).
Other IL6 Antibody Products
Reactivity: Human  
Application: B/N  
  • Slide 1
10395-mhK23-200
10395-mhK23-500
200 µg 
500 µg 
Add to Cart
Reactivity: Human  
Application: B/N  
  • Slide 1
10395-R508-200
10395-R508-500
200 µg 
500 µg 
Add to Cart
Reactivity: Human  
Application: IHC-P  
  • Slide 1
  • Slide 1
10395-MM10-100
10395-MM10-50
10395-MM10-200
100 µg 
50 µg 
200 µg 
Add to Cart
Reactivity: Human  
Application: ELISA  WB  IP  
  • Slide 1
  • Slide 1
10395-T52-50
10395-T52-100
10395-T52-200
50 µg 
100 µg 
200 µg 
Add to Cart
Reactivity: Human  
Application: ELISA  WB  
  • Slide 1
10395-T48-100
10395-T48-50
10395-T48-200
100 µg 
50 µg 
200 µg 
Add to Cart
Reactivity: Human  
Application: ELISA  
    10395-RP01-100
    10395-RP01-200
    10395-RP01-400
    100 µg 
    200 µg 
     
    Add to Cart
    Reactivity: Human  
    Application: ELISA  
      10395-MM02-50
      10395-MM02-100
      10395-MM02-200
      50 µg 
      100 µg 
      200 µg 
      Add to Cart
      Reactivity: Human  
      Application: ELISA  WB  
      • Slide 1
      10395-RP03-100
      10395-RP03-50
      10395-RP03-200
      100 µg 
      50 µg 
      200 µg 
      Add to Cart
      Reactivity: Human  
      Application: ELISA  
        10395-R057-50
        10395-R057-100
        50 µg 
        100 µg 
        Add to Cart
        Reactivity: Human  
        Application: B/N  
          10395-MK23-200
          10395-MK23-500
          200 µg 
          500 µg 
          Add to Cart
          Reactivity: Human  
          Application: ELISA  
            10395-T16-100
            10395-T16-50
            10395-T16-200
            100 µg 
            50 µg 
            200 µg 
            Add to Cart
            Reactivity: Mouse  
            Application: ELISA  WB  
            • Slide 1
            50136-T48-200
            50136-T48-50
            50136-T48-100
            200 µg 
            50 µg 
            100 µg 
            Add to Cart
            Reactivity: Mouse  
            Application: ELISA  
              50136-RP01-400
              50136-RP01-200
              50136-RP01-100
               
              200 µg 
              100 µg 
              Add to Cart
              Reactivity: Rat  
              Application: ELISA  
                80076-R007-50
                80076-R007-100
                50 µg 
                100 µg 
                Add to Cart
                Reactivity: Rat  
                Application: ELISA  
                  80076-T16-50
                  80076-T16-200
                  80076-T16-100
                  50 µg 
                  200 µg 
                  100 µg 
                  Add to Cart
                  Reactivity: Rhesus  
                  Application: ELISA  
                    90197-RP01-200
                    90197-RP01-100
                    90197-RP01-400
                    200 µg 
                    100 µg 
                     
                    Add to Cart
                    Reactivity: Sus scrofa (Pig)  
                    Application: ELISA  
                      62006-RP01-100
                      62006-RP01-400
                      62006-RP01-200
                      100 µg 
                       
                      200 µg 
                      Add to Cart
                      Reactivity: Sus scrofa (Pig)  
                      Application: ELISA  
                        62006-T16-200
                        62006-T16-100
                        62006-T16-50
                        200 µg 
                        100 µg 
                        50 µg 
                        Add to Cart
                        IL6/IL-6/Interleukin-6 Background

                        Interleukin-6 (IL-6) is a multifunctional α-helical cytokine that regulates cell growth and differentiation of various tissues, which is known particularly for its role in the immune response and acute phase reactions. IL-6 protein is secreted by a variety of cell types including T cells and macrophages as phosphorylated and variably glycosylated molecule. It exerts actions through the its heterodimeric receptor composed of IL-6R that lacks the tyrosine/kinase domain and binds IL-6 with low affinity, and ubiquitously expressed glycoprotein 130 (gp130) that binds the IL-6. IL-6R complex with high affinity and thus transduces signals. IL-6 is also involved in hematopoiesis, bone metabolism, and cancer progression, and has been defined an essential role in directing transition from innate to acquired immunity.

                        Cynomolgus IL6/IL-6/Interleukin-6 References
                      • Heinrich PC. et al. (2003). Principles of interleukin-6-type cytokine signalling and its regulation. Biochem J. 374: 1-20.
                      • Rose-John S, et al. (2007) The IL-6/sIL-6R complex as a novel target for therapeutic approaches. Expert Opin Ther Targets. 11(5): 613-24.
                      • Dinh W, et al. (2009) Elevated plasma levels of TNF-alpha and interleukin-6 in patients with diastolic dysfunction and glucose metabolism disorders. Cardiovasc Diabetol. 8:58.
                      • Product nameProduct name
                        Size / Price
                        Catalog: 90197-RP02-50
                        List Price: 
                        Price:      (You Save: )
                        All information of our products is subject to change without notice. Please refer to COA enclosed in shipped package for the newest information.
                        Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"