IL37 / IL1F7 / IL-1H4 Protein Price Inquiry ( Available Sizes )
IL37 / IL1F7 / IL-1H4 Protein Product Information
||IL37,FIL1, FIL1(ZETA), FIL1Z, IL-1F7, IL-1H, IL-1H4, IL-1RP1, IL-37, IL1F7, IL1H4, IL1RP1
||A DNA sequence encoding the mature form of human IL1F7 isoform A (Q9NZH6-2) (Lys 27-Asp 192 ) was expressed and purified, with an initial Met.
IL37 / IL1F7 / IL-1H4 Protein QC Testing
||> 96 % as determined by SDS-PAGE.
IL37 / IL1F7 / IL-1H4 protein
||Please contact us for more information.
||Samples are stable for up to twelve months from date of receipt at -70℃
|Predicted N terminal:
||The recombinant human IL1F7 consisting of 167 amino acids and has a calculated molecular mass of 18.7 KDa. It migrates as an 25 kDa band in SDS-PAGE under reducing conditions.
||Lyophilized from sterile PBS, pH 7.4
- Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
- Please contact us for any concerns or special requirements.
IL37 / IL1F7 / IL-1H4 Protein Usage Guide
||Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
||A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
IL37 / IL1F7 / IL-1H4 Protein Related Products & Topics
IL37 / IL1F7 / IL-1H4 Protein Description
Interleukin 1 family member 7, or interleukin 37 (IL1F7 / IL37 / IL-1H4) is a secretory protein belonging to the Interleukin 1 family. IL-1F7 was localized in human peripheral monocytic cells. It has been localized the expression of IL-1F7b protein in discrete cell populations including plasma cells and tumor cells. These data suggest that IL-1F7 may be involved in immune response, inflammatory diseases and / or cancer. Through constructing an adenoviral vector that allows high level expression in murine and human cells, it has been demonstrated that the ability of adenovirus-mediated gene transfer of IL1F7 to induce an IL-12- and Fas ligand-dependent anti-tumor response. Complete inhibition of tumor growth was observed following multiple injections of IL1F7 in the most animals. These results suggest that IL1F7 could play a role in both innate and adaptive immune responses, similar to IL-18. Moreover, IL1F7 could be useful for cancer gene therapy.
- Gao W. et al., 2003, J Immunol. 170 (1): 107-13.
- Bufler P. et al., 2002, Proc Natl Acad Sci. 99 (21): 13723-8.
- Kumar S. et al., 2002, Cytokine. 18 (2): 61-71.