Anti-IL-37 Antibody

Cat: 10155-RP01

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All IL-37 Reagents

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All IL-37 Reagents

Anti-IL-37 Antibody (Rabbit Polyclonal antibody) General Information

Product name
Anti-IL-37 Antibody
Validated applications
Species reactivity
Reacts with: Human
Human IL-37
Recombinant Human IL37 / IL1F7 / IL-1H4 protein (Catalog#10155-HNAE)
Produced in rabbits immunized with purified, recombinant Human IL37 / IL1F7 / IL-1H4 (rh IL37 / IL1F7 / IL-1H4; Catalog#10155-HNAE; Q9NZH6-2; Lys27-Asp192). Total IgG was purified by Protein A affinity chromatography.
Polyclonal Rabbit IgG
Protein A
0.2 μm filtered solution in PBS
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

Anti-IL-37 Antibody (Rabbit Polyclonal antibody) Validated Applications

Application Dilution Notes
ELISA 1:1000-1:2000  

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-IL-37 Antibody Alternative Names

Anti-FIL1 Antibody;Anti-FIL1(ZETA) Antibody;Anti-FIL1Z Antibody;Anti-IL-1F7 Antibody;Anti-IL-1H Antibody;Anti-IL-1H4 Antibody;Anti-IL-1RP1 Antibody;Anti-IL-37 Antibody;Anti-IL1F7 Antibody;Anti-IL1H4 Antibody;Anti-IL1RP1 Antibody;Anti-IL37 Antibody

IL-37 Background Information

Interleukin 1 family member 7, or interleukin 37 (IL1F7 / IL37 / IL-1H4) is a secretory protein belonging to the Interleukin 1 family. IL-1F7 was localized in human peripheral monocytic cells. It has been localized the expression of IL-1F7b protein in discrete cell populations including plasma cells and tumor cells. These data suggest that IL-1F7 may be involved in immune response, inflammatory diseases and / or cancer. Through constructing an adenoviral vector that allows high level expression in murine and human cells, it has been demonstrated that the ability of adenovirus-mediated gene transfer of IL1F7 to induce an IL-12- and Fas ligand-dependent anti-tumor response. Complete inhibition of tumor growth was observed following multiple injections of IL1F7 in the most animals. These results suggest that IL1F7 could play a role in both innate and adaptive immune responses, similar to IL-18. Moreover, IL1F7 could be useful for cancer gene therapy. 
Full Name
interleukin 37
  • Gao W, et al. (2003) Innate immunity mediated by the cytokine IL-1 homologue 4 (IL-1H4/IL-1F7) induces IL-12-dependent adaptive and profound antitumor immunity. J Immunol. 170 (1): 107-13.
  • Bufler P, et al. (2002) A complex of the IL-1 homologue IL-1F7b and IL-18-binding protein reduces IL-18 activity. Proc Natl Acad Sci. 99 (21): 13723-8.
  • Kumar S, et al. (2002) Interleukin-1F7B (IL-1H4 / IL-1F7) is processed by caspase-1 and mature IL-1F7B binds to the IL-18 receptor but does not induce IFN-gamma production. Cytokine. 18 (2): 61-71.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-IL-37 Antibody Rabbit Polyclonal ELISA 10155-T16
    Anti-IL-37 Antibody Mouse Monoclonal ELISA,ELISA(Cap) 10155-MM20
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