Anti-IL3 Antibody

Cat: 11858-T16
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Anti-IL3 Antibody (Rabbit Polyclonal antibody) General Information
Product name
Anti-IL3 Antibody
Validated applications
ELISA
Species reactivity
Reacts with: Human
Specificity
Human IL3
Immunogen
Recombinant Human IL3 / IL-3 protein (Catalog#11858-H08B)
Preparation
Produced in rabbits immunized with purified, recombinant Human IL3 / IL-3 (rh IL3 / IL-3; Catalog#11858-H08B; NP_000579.2; Met1-Phe152). IL3 / IL-3 specific IgG was purified by Human IL3 / IL-3 affinity chromatography.
Source
Polyclonal Rabbit IgG
Purification
Protein A & Antigen Affinity
Formulation
0.2 μm filtered solution in PBS
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-IL3 Antibody (Rabbit Polyclonal antibody) Validated Applications
Application Dilution Notes
ELISA 1:5000-1:10000  

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-IL3 Antibody Alternative Names
Anti-IL-3 Antibody;Anti-Interleukin-3 Antibody;Anti-MCGF Antibody;Anti-MULTI-CSF Antibody
IL3 Background Information

IL3 (interleukin 3), also known as IL-3, is a potent growth promoting cytokine which belongs to the IL-3 family. IL3/IL-3 also belongs to the group of interleukins. Interleukins are produced by a wide variety of body cells. The function of the immune system depends in a large part on interleukins, and rare deficiencies of a number of them have been described, all featuring autoimmune diseases or immune deficiency. The majority of interleukins are synthesized by helper CD4+ T lymphocytes, as well as through monocytes, macrophages, and endothelial cells. They promote the development and differentiation of T, B, and hematopoietic cells. IL3/IL-3 is capable of supporting the proliferation of a broad range of hematopoietic cell types. It is involved in a variety of cell activities such as cell growth, differentiation and apoptosis. IL3/IL-3 has been shown to also possess neurotrophic activity, and it may be associated with neurologic disorders.

Full Name
interleukin 3
References
  • Meyer CG, et al.. (2011) IL3 variant on chromosomal region 5q31-33 and protection from recurrent malaria attacks. Hum Mol Genet. 20(6):1173-81.
  • Zambrano A, et al. (2010) IL-3 controls tau modifications and protects cortical neurons from neurodegeneration. Curr Alzheimer Res. 7(7):615-24.
  • Dentelli P, et al.. (2011) IL-3 is a novel target to interfere with tumor vasculature. Oncogene. 30(50):4930-40.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-IL3 Antibody Rabbit Polyclonal ELISA,IHC-P 80235-RP02
    Anti-IL3 Antibody Rabbit Polyclonal ELISA 80235-T16
    Anti-IL3 Antibody Mouse Monoclonal ELISA 80235-MM03
    Anti-IL3 Antibody Rabbit Polyclonal ELISA 80235-RP01
    Anti-IL3 Antibody Rabbit Monoclonal ELISA 80235-R003
    Anti-IL3 Antibody Rabbit Polyclonal IHC-P 100316-T08
    Anti-IL3 Antibody Mouse Monoclonal ELISA 11858-MM22
    Anti-IL3 Antibody Rabbit Polyclonal ELISA 11858-RP01
    Anti-IL3 Antibody Mouse Monoclonal ELISA(Det) 11858-MM35
    Anti-IL3 Antibody Mouse Monoclonal ELISA(Cap) 11858-MM07
    Anti-IL3 Antibody Rabbit Monoclonal ELISA 11858-R001
    Anti-IL3 Antibody Rabbit Polyclonal WB,ELISA 11858-T48
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