|Catalog||Size (Price)||Quantity||In Stock||Operation||Other Information|
Interleukin 2 receptor, gamma Protein Datasheet
IL2RG / CD132 Protein Price Inquiry ( Available Sizes )
IL2RG / CD132 Protein Product Information
A DNA sequence encoding the human IL2RG(P31785) (Met1-Asn254 ) was expressed, fused with the Fc region of human IgG1 at the C-terminus.
|Expression Host:||Human Cells|
IL2RG / CD132 Protein QC Testing
|Purity:||> 99 % as determined by SDS-PAGE||SDS-PAGE:
IL2RG / CD132 protein
|Endotoxin:||< 1.0 EU per μg of the protein as determined by the LAL method|
|Stability:||Samples are stable for up to twelve months from date of receipt at -70℃|
|Predicted N terminal:||Leu 23|
The recombinant human IL2RG/Fc is a disulfide-linked homodimer. The reduced monomer comprises 473 amino acids and has a predicted molecular mass of 54.4 kDa. The apparent molecular mass of the protein is approximately 71 kDa in SDS-PAGE under reducing conditions.
|Formulation:||Lyophilized from sterile PBS, pH7.4.
IL2RG / CD132 Protein Usage Guide
|Storage:||Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.|
|Reconstitution:||A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.|
IL2RG / CD132 Protein Related Products & Topics
|Molecule||Species||Description //For Detailed Info. and Price------CLICK!||Cat. No|
|CD132/IL2RG||Human||IL2RG / CD132 Protein, Recombinant||10555-H02H|
|CD132/IL2RG||Human||IL2RG / CD132 Protein, Recombinant||10555-H08B|
|CD132/IL2RG||Mouse||CD132/IL2RG/Fc Protein, Recombinant||50087-M03H|
|CD132/IL2RG||Mouse||CD132/IL2RG Protein, Recombinant||50087-M08H|
|CD132/IL2RG||Rat||IL2RG / CD132 Protein, Recombinant||80197-R02H|
|CD132/IL2RG||Rat||IL2RG / CD132 Protein, Recombinant||80197-R08H|
|Molecule||Application||Description //For Detailed Info. and Price------CLICK!||Cat. No|
|Mouse CD132/IL2RG||WB, ELISA||CD132 / IL2RG Antibody||50087-RP01|
|Mouse CD132/IL2RG||WB, ELISA||CD132 / IL2RG Antibody (Antigen Affinity Purified)||50087-RP02|
IL2RG / CD132 Protein Description
The interleukin 2 receptor (IL-2R) is a heterotrimeric protein expressed on the surface of certain immune cells, such as lymphocytes, which binds and responds to the cytokine IL-2. Three distinct chains of IL-2R, termed as α, β and γ, which are non-covalently associated are identified. The α and β chains are involved in binding IL-2, while signal transduction following cytokine interaction is carried out by the γ chain, along with the β subunit which are members of the type I cytokine receptor family. The α chain of the IL-2R can bind to the β chain before receptor interaction with IL-2. The γ chain alone has a very weak affinity for IL-2, but after the ligand is bound to the α/β heterodimer, the γ chain becomes recruited to the complex to form a very stable macromolecular quaternary ligand/receptor complex. It is proposed that the γ chain is common to the IL2, IL4, IL7, IL21 and probably also the IL13 receptors.
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- Johnson K. et al., 1994, Eur Cytokine Netw. 5 (1): 23-34.