|Catalog||Size (Price)||Quantity||In Stock||Operation||Other Information|
Interleukin 20 receptor beta Protein Datasheet
IL20RB Protein Price Inquiry ( Available Sizes )
IL20RB Protein Product Information
A DNA sequence encoding the rat IL20RB (B8K1X9) (Met1-Pro227) was expressed, fused with the Fc region of human IgG1 at the C-terminus.
|Expression Host:||Human Cells|
IL20RB Protein QC Testing
|Purity:||> 70% as determined by SDS-PAGE||SDS-PAGE:
|Endotoxin:||< 1.0 EU per μg of the protein as determined by the LAL method|
|Stability:||Samples are stable for up to twelve months from date of receipt at -70℃|
|Predicted N terminal:||Phe 22|
The recombinant rat IL20RB/Fc is a disulfide-linked homodimer. The reduced monomer comprises 447 amino acids and has a predicted molecular mass of 50.2 kDa. The apparent molecular mass of the protein is approximately 61 kDa in SDS-PAGE under reducing conditions.
|Formulation:||Lyophilized from sterile PBS, pH7.4.
IL20RB Protein Usage Guide
|Storage:||Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.|
|Reconstitution:||A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.|
IL20RB Protein Related Products & Topics
|Molecule||Species||Description //For Detailed Info. and Price------CLICK!||Cat No|
|IL20RB||Rat||IL20RB Protein, Recombinant||80187-R02H|
|IL20RB||Rat||IL20RB Protein, Recombinant||80187-R08H|
IL20RB Protein Description
IL20RB contains 2 fibronectin type-III domains and belongs to the type II cytokine receptor family. There are two kinds of type II cytokine receptors : cytokine receptors that bind type I and type II interferons; cytokine receptors that bind members of the interleukin-10 family (interleukin-10, interleukin-20 and interleukin-22). Type II cytokine receptors are heterodimers or multimers with a high and a low affinity component. These receptors are related predominantly by sequence similarities in their extracellular portions that are composed of tandem Ig-like domains. The intracellular domain of type II cytokine receptors is typically associated with a tyrosine kinase belonging to the Janus kinase (JAK) family. IL20RB is widely expressed with highest levels in skin and testis and highly expressed in psoriatic skin. The IL20RA/IL20RB dimer is a receptor for IL19, IL20 and IL24. The IL22RA1/IL20RB dimer is a receptor for IL20 and IL24.
- Zhu H. et al., 2009, Hepatobiliary Pancreat Dis Int. 8 (4): 402-6.
- Logsdon NJ. et al., 2012, Acta Crystallogr Sect F Struct Biol Cryst Commun. 68 (1): 89-92.
- Kingo K. et al., 2008, Genes Immun. 9 (5): 445-51.