All IL20RB reagents are produced in house and quality controlled, including 4 IL20RB Antibody, 47 IL20RB Gene, 4 IL20RB Lysate, 4 IL20RB Protein, 3 IL20RB qPCR. All IL20RB reagents are ready to use.
Recombinant IL20RB proteins are expressed by HEK293 Cells with fusion tags as C-human IgG1-Fc, C-His.
IL20RBantibodies are validated with different applications, which are WB, ELISA.
IL20RBcDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each IL20RB of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.
IL20RB belongs to the type II cytokine receptor family. There are two kinds of type II cytokine receptors : cytokine receptors that bind type I and type II interferons; cytokine receptors that bind members of the interleukin-10 family (interleukin-10, interleukin-20 and interleukin-22). Type II cytokine receptors are similar to type I cytokine receptors except they do not possess the signature sequence WSXWS that is characteristic of type I receptors. They are expressed on the surface of certain cells, which bind and respond to a select group of cytokines. These receptors are related predominantly by sequence similarities in their extracellular portions that are composed of tandem Ig-like domains. The intracellular domain of type II cytokine receptors is typically associated with a tyrosine kinase belonging to the Janus kinase (JAK) family. IL20RB and IL20RA (MIM 605620) form a heterodimeric receptor for interleukin-20.