IL20RA / IL-20RA Protein & Antibody

Interleukin 20 Receptor, Alpha

IL20RA / IL-20RA Products

IL20RA / IL-20RA Protein, Recombinant

Molecule	Species	Description	Cat. No
IL20RA/IL-20RA	Human	IL20RA/IL-20RA Protein, Recombinant	10397-H08H

IL20RA / IL-20RA Antibody

Molecule	Application	Description	Cat. No
Human IL20RA/IL-20RA	WB, ELISA	Mouse Monoclonal Antibody	10397-MM06
Human IL20RA/IL-20RA	ELISA	Rabbit Monoclonal Antibody	10397-R005
Human IL20RA/IL-20RA	WB, ELISA, IHC-P	IL20RA / IL-20RA Antibody	10397-R024
Human IL20RA/IL-20RA	WB	Rabbit Monoclonal Antibody	10397-R030
Human IL20RA/IL-20RA	WB, ELISA, IHC-P	IL20RA / IL-20RA Antibody	10397-R038
Human IL20RA/IL-20RA	WB, ELISA	Rabbit Monoclonal Antibody	10397-RP01
Human IL20RA/IL-20RA	WB, ELISA	Rabbit Polyclonal Antibody (Antigen Affinity Purified)	10397-RP02

IL20RA / IL-20RA ELISA Kit

Molecule	Application	Description	Cat. No
Human IL20RA/IL-20RA	ELISA	IL20RA/IL-20RA ELISA Kit	SEK10397

IL20RA / IL-20RA cDNA Clone

Molecule	Species	Description	Cat. No
IL20RA/IL-20RA	Human	Homo sapiens IL20RA/IL-20RA cDNA Clone(NM_014432.2)	HG10397-M
IL20RA/IL-20RA	Rat	IL20Ra cDNA Clone / ORF Clone	RG80227-G

IL20RA / IL-20RA Alternative Names

IL20RA, RP11-204P2.1, FLJ40993, IL-20R1, ZCYTOR7 [Homo sapiens]

Il20ra, E230031K19 [Mus musculus]

IL20RA / IL-20RA Related Areas

Cancer>>Angiogenesis>>Cytokines/Chemokines in Angiogenesis>>IL20RA / IL-20RA

Immunology>>Cytokine & Receptor>>Interleukin & Receptor>>IL-10/Interferon Family>>IL20RA / IL-20RA

IL20RA / IL-20RA Background

Interleukin 20 receptor, alpha subunit (IL20RA/IL-20RA) also known as IL-20 receptor subunit alpha, Cytokine receptor class-II member 8, interleukin-20 receptor I, and interleukin-20 receptor subunit alpha, is a subunit for the interleukin-20 receptor. IL20RA/IL-20RA belongs to the type II cytokine receptor family. This cytokine is a receptor for interleukin 20 (IL20), a cytokine that may be involved in epidermal function. The receptor of IL20 is a heterodimeric receptor complex consisting of this protein and interleukin 20 receptor beta (IL20B). IL20RA forms heterodimer with IL20RB, and the complex serves as a receptor for IL19, IL20 and IL24. All three are capable of signaling through IL-20RA/IL-20RB complex. The ligand binding to receptor B creating a high-affinity binding site for the receptor A which is recruited to complete the complex. In addition, IL20RA also forms a heterodimer with the unique and specific receptor IL10RB and functions as the receptor for IL26. IL20RA is widely expressed with highest levels in skin, testis and brain. The expression of both IL20RA and IL20RB is found to be upregulated in psoriatic skin lesions on keratinocytes.

IL20RA / IL-20RA Related Studies

1. Parrish-Novak J, et al. (2002) Interleukins 19, 20, and 24 signal through two distinct receptor complexes. Differences in receptor-ligand interactions mediate unique biological functions. J Biol Chem. 277(49): 47517-23.
2. Kingo K, et al. (2008) Association analysis of IL20RA and IL20RB genes in psoriasis. Genes Immun. 9(5): 445-51.
3. Blumberg H, et al. (2001) Interleukin 20: discovery, receptor identification, and role in epidermal function. Cell. 104(1): 9-19.