Anti-ST2/IL-1 RL1 Antibody


Anti-ST2/IL-1 RL1 Antibody (Mouse Monoclonal antibody) General Information

Product name
Anti-ST2/IL-1 RL1 Antibody
Validated applications
Species reactivity
Reacts with: Human
Human ST2/IL-1 RL1
No cross-reactivity in ELISA and WB with
Human IL1R1 / CD121a
Human IL1R2 / IL1RB / CD121b
Human IL1F3 / IL1RA
Human cell lysate (293 cell line)
Recombinant Human IL1RL1 protein (Catalog#10105-H08H)
This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human IL1RL1 extracellular domain (rh IL1RL1; Catalog#10218-HCCH; Met 1-Phe 328; NP_003847.2). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
Monoclonal Mouse IgG1 Clone #1E5F10D3
Protein A
0.2 μm filtered solution in PBS
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Anti-ST2/IL-1 RL1 Antibody (Mouse Monoclonal antibody) Validated Applications

Application Dilution
ELISA 1:1000-1:2000
Please Note: Optimal concentrations/dilutions should be determined by the end user.

Anti-ST2/IL-1 RL1 Antibody: Alternative Names

Anti-DER4 Antibody; Anti-FIT-1 Antibody; Anti-IL1RL1 Antibody; Anti-IL33R Antibody; Anti-IL‑1 R4 Antibody; Anti-ST2 Antibody; Anti-ST2L Antibody; Anti-ST2V Antibody; Anti-T1 Antibody

ST2/IL-1 RL1 Background Information

IL-1 receptor–like 1 (IL1RL1) is a membrane receptor involved in TH2 inflammatory responses and eosinophilia. It has previously been described that levels of the interlukin-1 like 1 (IL1RL1) protein can be used to diagnose cardiovascular disease and determine the prognosis for a patient with cardiovascular disease. The ligand for IL1RL1 has been described, and named IL-33. Mutants in IL1RL1 have been associated with blood eosinophil counts in a genome-wide association study and with asthma in family-based and case-control studies. As an important mediator involved in many immune and inflammatory responses, this cytokine has been implicated as a regulator of both the development and effector phases of type 2 helper T cell responses, and as a negative feedback modulator of macrophage pro-inflammatory function. IL33 is a specific ligand of ST2L and induces production of Th2 cytokines.
Full Name
interleukin 1 receptor-like 1
  • Savenije OE, et al. (2011) Interleukin-1 receptor-like 1 polymorphisms are associated with serum IL1RL1-a, eosinophils, and asthma in childhood. J Allergy Clin Immunol. 127(3): 750-6.
  • Li H, et al. (2000) The cloning and nucleotide sequence of human ST2L cDNA. Genomics. 67(3): 284-90.
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