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Cynomolgus IL18RAP Protein (His Tag)
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Cynomolgus IL18RAP Protein (His Tag) (Cytokine) PDF Download

Catalog   Size (Price) Quantity In Stock Operation
90122-C08H  
YES   
 

Protein Production & Purification Service | Recombinant Cytokines & Growth Factors

Interleukin 18 receptor accessory protein Protein Datasheet

 

IL18RAP Protein Price Inquiry ( Available Sizes )

IL18RAP Protein Product Information

Synonym : IL18RAP
Protein Construction:

A DNA sequence encoding the cynomolgus IL18RAP (F7HHC1) (Met1-Arg356) was expressed, fused with a polyhistidine tag at the C-terminus.

Source: Cynomolgus
Expression Host: Human Cells

IL18RAP Protein QC Testing

Purity: > 95 % as determined by SDS-PAGE SDS-PAGE:
SDS-PAGE

IL18RAP protein

Bio-activity:

Measured by its binding ability in a functional ELISA.
Immobilized Cynomolgus 18RAP-His at 10 μg/ml (100 μl/well) can bind biotinylated Cynomolgus IL18 (Cat:90011-C07E) with a linear range of 0.16-2.5 μg/ml.
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method
Stability: Samples are stable for up to twelve months from date of receipt at -70℃
Predicted N terminal: Phe 20
Molecular Mass:

The recombinant cynomolgus IL18RAP comprises 578 amino acids and has a calculated molecular mass of 65.4 KDa.The apparent molecular mass of the protein is approximately 57 KDa respectively in SDS-PAGE.

Formulation: Lyophilized from sterile PBS, pH7.4.
  1. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
  2. Please contact us for any concerns or special requirements.

IL18RAP Protein Usage Guide

Storage: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

IL18RAP Protein Related Products & Topics

IL18RAP Protein Description

Interleukin 18 receptor accessory protein, also known as IL18RAP, IL1R7 and CDw218b, is a single-pass type I  membrane protein. It is member of the interleukin-1 receptor family. IL18RAP contains 2 Ig-like C2-type (immunoglobulin-like) domains and 1 TIR domain. IL18RAP is strongly expressed in peripheral blood leukocytes, spleen, lung, and, to a lesser extent, in colon. It is not expressed in any other tissue tested. IL18RAP is also strongly expressed in T-cells polarized with IL12 and specifically coexpressed with IL18R1 in Th1 cells. IL18RAP is an accessory subunit of the heterodimeric receptor for IL18. This protein enhances the IL18 binding activity of IL18R1, the ligand binding subunit of IL18 receptor. The coexpression of IL18R1 and IL18RAP is required for the activation of NF-κB and MAPK8 (JNK) in response to IL18. Variants at IL18RAP have been linked to susceptibility to coeliac disease.

References

  1. Born TL. et al., 1998, J Biol Chem. 273 (45): 29445-50.
  2. Hillier LW. et al., 2005, Nature. 434: 724-31.
  3. Hunt KA. et al., 2008, Nat Genet. 40 (4): 395-402.
  4. Imami K. et al., 2008, Anal Sci. 24: 161-6.
 

All IL-1 Proteins

Product name Product name
IL18 Protein (Native) IL-1 alpha / IL1A / IL1F1 Protein
IL18BPa Protein Mouse IL1R1 / CD121a Protein (His Tag)
IL18BPa Protein (His Tag) Cynomolgus IL-1 beta / IL1B Protein (Native)
IL1F5 / IL36RN Protein (Native) IL36B / IL1F8 Protein (Native)
IL1R2 / CD121b Protein IL1F6 / IL36A Protein (Native)
IL1RL1 / DER4 Protein Mouse IL-1R8 / IL1RAPL1 Protein
IL1RL1 / DER4 Protein Canine IL-1 beta / IL1B Protein (Native)
IL1R9 Protein IL36G / IL1F9 Protein (Native)
IL1RA / IL1F3 Protein Mouse IL1F8 / IL36b Protein Native
IL1RA / IL1F3 Protein (Native) IL37 / IL1F7 / IL-1H4 Protein Native
IL-1 alpha / IL1A / IL1F1 Protein Mouse IL1R1 / CD121a Protein
IL33 / Interleukin-33 / NF-HEV Protein (Native) Canine IL33 / Interleukin-33 / NF-HEV Protein (Native)
Mouse IL-18R1 Protein IL36B / IL1F8 Protein (His Tag)
IL-1R8 Protein IL1F6 / IL36A Protein (His Tag)
Mouse SIGIRR Protein Rat IL18R1 Protein
IL1R8 Protein (His Tag) Rat IL1R2 / IL1RB / CD121b Protein (His Tag)
IL1R3 Protein IL36G / IL1F9 (aa 18-169) Protein (His Tag)
IL1R1 / CD121a Protein IL36G / IL1F9 (aa 18-169) Protein
IL1R1 / CD121a Protein (His Tag) IL1F6 / IL36 (aa 6-158) Protein
IL-1 beta / IL1B Protein (Native) Mouse IL-18 Protein (Native)
Mouse IL18BP Protein (His Tag) Mouse IL1R2 / CD121b Protein
IL18RAP / IL1R7 Protein Mouse IL1R2 / CD121b Protein (His Tag)
IL18R1 / CD218a Protein (His Tag) Rat IL1RN / IL1RA Protein
IL1R3 / IL1RAP Protein (His Tag) Cynomolgus IL18RAP Protein
IL18R1 / CD218a Protein Cynomolgus IL18RAP Protein (His Tag)
IL1RL1 / ST2 Protein (His Tag) Rat IL1R2 / IL1RB / CD121b Protein
IL1R2 / IL1RB / CD121b Protein (His Tag) Cynomolgus IL1R2 / IL1RB Protein
Mouse IL18R1 / CD218a Protein (His Tag) Mouse IL18 / IL-18 Protein
IL18RAP / IL1R7 Protein (His Tag) IL18 / Interleukin 18 / IGIF Protein (GST Tag)
Mouse IL-1 alpha / IL1A / IL1F1 Protein (Native) IL1R1 / CD121a Protein
Mouse IL1F5 / IL1RP3 Protein (Native) IL1R2 / IL1RB / CD121b Protein
IL1R9 / IL1RAPL2 / IL1 Receptor 9 Protein (His Tag) SIGIRR / TIR8 Protein
Rat IL-1 beta / IL1B ( pro form ) Protein (His Tag) Cynomolgus IL1R1 Protein
SIGIRR / TIR8 Protein (His Tag) Cynomolgus IL1R1 Protein (His Tag)
Cynomolgus IL-18 / IL-1F4 Protein (His Tag) Canine IL18R1 Protein
Mouse IL-1F6 / IL-1 epsilon Protein (Native) Canine IL1R2 / IL1RB Protein
IL-1 beta / IL1B (pro form) Protein (His Tag) Rat IL18R1 Protein (His Tag)
Rat IL1R1 / CD121a Protein (His Tag) Mouse IL36G / IL1F9 Protein (His Tag)
Mouse IL-1 beta / IL1B Protein (Native) Cynomolgus IL18R1 Protein
Rat IL1R1 / CD121a Protein Rabbit IL-1 beta / IL1B Protein
IL1RL1 / ST2 (isoform A) Protein (His Tag) Cynomolgus IL18R1 Protein (His Tag)
Rat IL-1 beta / IL1B (mature form) Protein (Native)  

All IL-1 Antibodies

Product name Product name
IL1RL1 / ST2 Antibody (Mouse Monoclonal Antibody) IL-18 Antibody (Antigen Affinity Purified)
IL1RL1 / ST2 Antibody SIGIRR / TIR8 Antibody
IL33 / Interleukin-33 / NF-HEV Antibody (Mouse Monoclonal Antibody) SIGIRR / TIR8 Antibody (Antigen Affinity Purified)
IL33 / Interleukin-33 / NF-HEV Antibody IL18 / Interleukin-18 Antibody
IL18BP / IL18BPa Antibody (Mouse Monoclonal Antibody) IL-1RA Antibody
IL18BP / IL18BPa Antibody IL-1R8 / IL1RAPL1 Antibody
IL18BP / IL18BPa Antibody IL-1R2 / CD121b Antibody
IL18BP / IL-18BP Antibody IL-1R9 / IL1RAPL2 Antibody (Antigen Affinity Purified)
IL18BP / IL18BPa Antibody (Antigen Affinity Purified) IL-1 beta / IL1B Antibody (Antigen Affinity Purified)
IL1R1 / CD121a Antibody IL-1F6 Antibody (Antigen Affinity Purified)
IL1R1 / CD121a Antibody (Antigen Affinity Purified) IL-1R1 / CD121a Antibody (Antigen Affinity Purified)
IL1RL1 / ST2 Antibody (Antigen Affinity Purified) IL-1 beta / IL1B Antibody (Antigen Affinity Purified)
IL18BP / IL-18BP Antibody (Antigen Affinity Purified) IL-33 Antibody
IL1R1 / CD121a Antibody (Mouse Monoclonal Antibody) IL-1RA Antibody (FITC)
IL18R1 / CD218a Antibody IL-1 alpha / IL-1F1 / IL1A Antibody (Antigen Affinity Purified)
IL18R1 / CD218a Antibody (Antigen Affinity Purified) IL18BP / IL18BPa Antibody
IL33 / Interleukin-33 / NF-HEV Antibody IL1F6 / IL36A Antibody
IL33 / Interleukin-33 / NF-HEV Antibody (Antigen Affinity Purified) IL-1 alpha / IL-1F1 / IL1A Antibody
IL1R3 / IL1RAP Antibody IL-1R1 / CD121a Antibody
IL1R2 / IL1RB / CD121b Antibody IL-33 Antibody
IL1R2 / IL1RB / CD121b Antibody (Antigen Affinity Purified) IL-33 Antibody
IL-1 beta / IL1B / IL1F2 Antibody IL-33 Antibody (FITC)
IL-1 beta / IL1B / IL1F2 Antibody (Antigen Affinity Purified) IL1F6 / IL36A Antibody
IL1R1 / CD121a Antibody IL-18 Antibody
IL18R1 / IL1RRP / CD218a Antibody IL37 / IL1F7 / IL-1H4 Antibody
IL18R1 / IL1RRP / CD218a Antibody (Antigen Affinity Purified) IL-1F5 Antibody
IL18R1 / CD218a Antibody IL-1RAcP / IL-1R3 Antibody (FITC)
IL18BP / IL-18BP Antibody IL-1RAcP / IL-1R3 Antibody (PE)
IL18BP / IL-18BP Antibody IL-1RA Antibody (PE)
IL1R2 / IL1RB / CD121b Antibody IL-33 Antibody (PE)
IL1R2 / IL1RB / CD121b Antibody IL-33 Antibody (FITC)
IL1R2 / IL1RB / CD121b Antibody SIGIRR / TIR8 Antibody
IL18R1 / CD218a Antibody IL1R1 / CD121a Antibody
IL1RA / IL1F3 Antibody IL1R1 / CD121a Antibody
IL-1 beta / IL1B / IL1F2 Antibody IL-1 beta / IL1B Antibody
IL18R1 Antibody IL-1 beta / IL1B Antibody
IL1RL1 Antibody IL-1R1 / CD121a Antibody
IL1RL1 Antibody IL-1R1 / CD121a Antibody
IL-1RAcP / IL-1R3 Antibody (Antigen Affinity Purified) IL-1RA Antibody (Antigen Affinity Purified)
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"