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IL17RC Antibody ( Antigen Affinity Purified ) Datasheet
|Order or Inquire for IL17RC Antibody product||Quality antibodies||Antibody production services|
|Detection limit is 0.00975 ng/well in ELISA|
IL17RC Antibody Product Information
Recombinant Human IL17RC protein (Catalog#11747-H08B)
|Antibody Type :||Rabbit Polyclonal Antibody ( Antibody Purification Platform )|
|Ig Type :||
|Formulation :||0.2 μm filtered solution in PBS with 5% trehalose|
Produced in rabbits immunized with purified, recombinant Human IL17RC (rh IL17RC; Catalog#11747-H08B; NP_116121.2; Met 1-Ala 454). IL17RC specific IgG was purified by Human IL17RC affinity chromatography.
IL17RC Antibody Usage Guide
|Direct ELISA :||This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Human IL17RC. The detection limit for Human IL17RC is approximately 0.00975 ng/well.|
|Storage :||This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
IL17RC Antibody Related Products & Topics
|Molecule||Species||Description //For Detailed Info. and Price------CLICK!||Cat No|
|IL17RC||Human||IL17RC Protein, Recombinant||11747-H02H|
|IL17RC||Human||IL17RC (aa 1-454) Protein, Recombinant||11747-H08B|
|Molecule||Application||Description //For Detailed Info. and Price------CLICK!||Cat No|
|Human IL17RC||ELISA||IL17RC Antibody||11747-RP01|
|Human IL17RC||ELISA||IL17RC Antibody (Antigen Affinity Purified)||11747-RP02|
IL17RC Antibody Background
Interleukin-17 receptor C (IL-17RC) is a single-pass transmembrane protein that shares similarity with the IL-17R. IL-17RC functions as a receptor for both IL-17A and IL-17F, both of which are considered as factors contributing to the progression of inflammatory and autoimmune diseases. IL-17A and IL-17F mediate inflammatory activities via the IL-17 receptor complex, comprised of the IL-17RA and IL-17RC subunits. Soluble version of IL-17RC should be an effective antagonist of IL-17A and IL-17F mediated inflammatory diseases. IL-17RC and IL-17RA have been found to be overexpressed in rheumatoid arthritis (RA) peripheral whole blood and their expression was detected locally in RA synovium. IL-17RC protein expression was significantly higher in androgen-independent prostate cancers than in androgen-dependent ones. This protein is differentially expressed in prostatic cells and cancer tissues and may play a negative or positive role in the initiation and progression of prostate cancer.
- Allen W. et al., 2010, Semin Immunopathol. 32 (1): 33-42.
- You ZB. et al., 2007, Neoplasia. 9 (6): 464-70.
- Zrioual S. et al., 2008, J Immunol. 180 (1):655-63.
- Kuestner RE. et al., 2010, J Immunol. 179 (8): 5462-73.