>Human Cell Expressed
>Cynomolgus IL17RA / IL17R Protein
|Catalog||Size (Price)||Quantity||In Stock||Operation||Other Information|
Interleukin 17 receptor A Protein Datasheet
IL17RA / IL17R Protein Price Inquiry ( Available Sizes )
- ≥1mg Bulk: Inquiring Price
IL17RA / IL17R Protein Product Information
A DNA sequence encoding the cynomolgus IL17RA (Met1-Trp320) was expressed, fused with the Fc region of human IgG1 at the C-terminus.
|Expression Host:||Human Cells|
IL17RA / IL17R Protein QC Testing
|Purity:||> 90 % as determined by SDS-PAGE||SDS-PAGE:
IL17RA / IL17R protein
|Endotoxin:||< 1.0 EU per μg of the protein as determined by the LAL method|
|Stability:||Samples are stable for up to twelve months from date of receipt at -70℃|
|Predicted N terminal:||Leu 33|
The recombinant cynomolgus IL17RA is a disulfide-linked homodimer. The reduced monomer comprises 529 amino acids and has a calculated molecular mass of 60.3 KDa.The apparent molecular mass of the protein is approximately 75-98 KDa respectively in SDS-PAGE.
|Formulation:||Lyophilized from sterile PBS, pH7.4.
IL17RA / IL17R Protein Usage Guide
|Storage:||Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.|
|Reconstitution:||A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.|
IL17RA / IL17R Protein Related Products & Topics
|Molecule||Species||Description //For Detailed Info. and Price------CLICK!||Cat. No|
|IL-17R/IL-17RA/CD217||Human||IL-17R/IL-17RA/CD217 Protein, Recombinant||10895-H03H|
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|IL-17R/IL-17RA||Cynomolgus||IL17RA / IL17R Protein, Recombinant||90127-C02H|
|Molecule||Application||Description //For Detailed Info. and Price------CLICK!||Cat. No|
|ELISA||IL-17R/IL-17RA/CD217 Antibody, Mouse MAb||10895-MM06|
|WB||IL-17R/IL-17RA/CD217 Antibody, Mouse MAb||10895-MM07|
|WB, ELISA||IL-17R/IL-17RA/CD217 Antibody, Rabbit MAb||10895-R012|
|WB, ELISA||IL-17R / IL-17RA Antibody (Antigen Affinity Purified)||50328-RP02|
IL17RA / IL17R Protein Description
Interleukin-17 receptor A, also known as IL-17 receptor A, IL-17RA, IL17RA and IL17R, is an ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A (IL17A). IL17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. IL17A binds to a type I cell surface receptor called IL17R of which there are at least three variants IL17RA, IL17RB, and IL17RC. IL17RA is a widely expressed glycoprotein that plays a central role in inflammatory responses. IL17R mRNA exhibits a broad tissue distribution, and has been detected in virtually all cells and tissues tested. The aa sequence of mouse IL17RA is 69% identical to the human IL17R. Within the extracellular domain, mouse IL17RA shares 72% aa sequence identity with human IL17RA. IL17RA associates with IL17RC to form a signaling receptor complex for IL17 and IL17F. Ligand and IL17RA ligation promotes T cell activation and the production of IL-6, G-CSF, SCF, and multiple proinflammatory chemokines.
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