All IL13RA2 reagents are produced in house and quality controlled, including 12 IL13RA2 Antibody, 53 IL13RA2 Gene, 8 IL13RA2 Lysate, 8 IL13RA2 Protein, 3 IL13RA2 qPCR. All IL13RA2 reagents are ready to use.
Recombinant IL13RA2 proteins are expressed by HEK293 Cells with fusion tags as C-human IgG1-Fc, C-His, C-human IgG1-Fc & His.
IL13RA2antibodies are validated with different applications, which are ELISA, FCM, IHC-P.
IL13RA2cDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each IL13RA2 of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.
Interleukin-13 receptor subunit alpha-2 (IL13RA2/IL-13RA2) is also known as also known as cluster of differentiation 213A2 (CD213A2), IL-13 receptor subunit alpha-2, IL-13R subunit alpha-2, and IL-13RA2. The IL13RA2 is often overexpressed in brain tumors, making Il13ra2 one of the vaccine targets for immunotherapy of glioma. IL13RA2/IL-13RA2 is a cancer-associated receptor that is present in greater than 80% of High Grade Astrocytomas (HGA) and has recently been recognized as a cytokine that predisposes breast cancer cells to metastasize. Expression of IL13Rα2 was rapidly lost from the surface of transduced cells grown in culture. The loss appeared to be related to ligands present in fetal bovine serum in the medium. None of the malignant glioma cell lines cultivated in vitro and tested to date exhibited the IL13Rα2 receptor. A recombinant virus (R5111) enters cells via its interaction with the IL13Rα2 receptor in a manner that cannot be differentiated from the interaction of wild-type virus with its receptors.