IL13RA1 Protein & Antibody (CD213a1)

Interleukin 13 Receptor, alpha 1 (Cluster of Differentiation 213a1)

IL13RA1 Products

IL13RA1 Protein, Recombinant

Molecule	Species	Description	Cat. No
IL-13RA1/CD213a1	Human	IL-13RA1/CD213a1/Fc Protein, Recombinant	10943-H03H
IL-13RA1/CD213a1	Human	IL-13RA1/CD213a1 Protein, Recombinant	10943-H08H
IL-13RA1/CD213a1	Mouse	IL-13RA1/CD213a1/Fc Protein, Recombinant	50088-M03H
IL-13RA1/CD213a1	Mouse	IL-13RA1/CD213a1 Protein, Recombinant	50088-M08H

  10943-H03H: Immobilized cynomolgus IL-13 at 4 μg/ml (100 μl/well) can bind human IL13RA1-Fc with a linear ranger of  0.156 - 2.5 μg/ml . Measured by its binding ability in a functional ELISA.

  10943-H08H: Immobilized human IL13RA1 at 4 μg/ml (100 μl/well) can bind human IL13 with a linear ranger of  0.156 - 2.5 μg/ml Measured by its binding ability in a functional ELISA.

IL13RA1 Antibody

Molecule	Application	Description	Cat. No
Human IL-13RA1/CD213a1	WB, ELISA	IL13RA1 Antibody, Mouse MAb	10943-MM06
Human IL-13RA1/CD213a1	ELISA	IL13RA1 Antibody, Rabbit MAb	10943-R026
Human IL-13RA1/CD213a1	WB	IL13RA1 Antibody, Rabbit MAb	10943-R038
Human IL-13RA1/CD213a1	WB, ELISA	Rabbit Polyclonal Antibody	10943-RP01
Human IL-13RA1/CD213a1	WB, ELISA	Rabbit Polyclonal Antibody (Antigen Affinity Purified)	10943-RP02
Mouse IL-13RA1/CD213a1	WB, ELISA	IL13RA1 Antibody, Rabbit MAb	50088-R122
Mouse IL-13RA1/CD213a1	WB, ELISA	Rabbit Polyclonal Antibody	50088-RP01
Mouse IL-13RA1/CD213a1	WB, ELISA	Rabbit Polyclonal Antibody (Antigen Affinity Purified)	50088-RP02

IL13RA1 ELISA Kit

Molecule	Application	Description	Cat. No
Human IL13RA1	ELISA	IL13RA1 ELISA Kit	SEK10943

IL13RA1 cDNA Clone

Molecule	Species	Description	Cat. No
IL-13RA1/CD213a1	Human	Homo sapiens IL-13RA1/CD213a1 cDNA Clone(NM_001560.2)	HG10943-M
IL-13RA1/CD213a1	Mouse	Mus musculus IL-13RA1/CD213a1 cDNA Clone	MG50088-M
IL-13RA1/CD213a1	Rat	Rat IL-13RA1/CD213a1 cDNA Clone	RG80186-G

IL13RA1 Related Areas

Stem Cell>>Hematopoietic Stem Cell (HSC)>>Hemangioblast>>Endothelial Cell Marker>>IL-13RA1/CD213a1

Cancer>>Angiogenesis>>Cytokines/Chemokines in Angiogenesis>>IL-13RA1/CD213a1

Immunology>>Cytokine & Receptor>>Interleukin & Receptor>>Other>>IL-13RA1/CD213a1

Immunology>>Cluster of Differentiation>>B Cell CD Antigen>> IL-13RA1/CD213a1

Immunology>>Cluster of Differentiation>>Monocyte/Macrophage CD Antigen>>Monocyte Markers>>IL-13RA1/CD213a1

Immunology>>Cluster of Differentiation>>T Cell CD Antigen>>Helper T Cells>>IL-13RA1/CD213a1

IL13RA1 Alternative Names

IL13RA1, CD213A1, RP13-128O4.2, IL-13Ra, NR4 [Homo sapiens]

Il13ra1, CD213a1, RP23-132G2.1, AI882074, IL-13r[a], Il13ra, NR4 [Mus musculus]

IL13RA1 Background

Interleukin 13 receptor, alpha 1, also known as IL13RA1/IL-13RA1 and CD213A1 (cluster of differentiation 213A1), is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. IL13RA1/IL-13RA1 serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4. IL13RA1/IL-13RA1 binds with low affinity to interleukin-13 (IL13). This subunit together with IL4RA can form a functional receptor for IL13. IL13RA1/IL-13RA1 also serves as an alternate accessory protein to the common cytokine receptor gamma chain for interleukin-4 (IL4) signaling, but cannot replace the function of IL2RG in allowing enhanced interleukin-2 (IL2) binding activity.

IL13RA1 Related Studies

1. Kawakami M, et al. (2002) Mutation and functional analysis of IL-13 receptors in human malignant glioma cells. Oncol Res. 12 (11-12): 459-67.
2. Umeshita-Suyama R, et al. (2000) Characterization of IL-4 and IL-13 signals dependent on the human IL-13 receptor alpha chain 1: redundancy of requirement of tyrosine residue for STAT3 activation. Int Immunol. 12 (11): 1499-509.
3. He JQ, et al. (2003) Polymorphisms in the IL13, IL13RA1, and IL4RA genes and rate of decline in lung function in smokers. Am J Respir. Cell Mol Biol. 28 (3): 379-85.