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Product Catalog
IL-13 / ALRH Antibody (Cytokine) 
| Catalog | Size (Price) | Quantity | In Stock | Operation | Other Information |
| 10369-R062 |
|
YES | 
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IL13 / ALRH Antibody Datasheet
 |
Order or Inquire for IL13 / ALRH Antibody product | Quality antibodies | Antibody production services | |
|
Detection limit is 0.0049 ng/well in ELISA |
IL13 / ALRH Antibody Product Information
| Immunogen : |
Recombinant Human IL13 / ALRH protein (Catalog#10369-H01H) |
| Antibody Type : | Rabbit Monoclonal Antibody ( Rabbit mAb Service Platform ) |
|
Clone ID : |
062 |
| Ig Type : |
Rabbit IgG |
| Formulation : | 0.2 μm filtered solution in PBS with 5% trehalose |
| Preparation : |
This antibody was obtained from a rabbit immunized with purified, recombinant Human IL13 / ALRH (rh IL13 / ALRH; Catalog#10369-H01H; AAK53823.1; Gly 21-Asn 132). |
IL13 / ALRH Antibody Usage Guide
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Specificity : |
Human IL13 / ALRH |
| Has cross-reactivity in ELISA with Cynomolgus IL13 |
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| Direct ELISA : | This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Human IL13. The detection limit for Human IL13 is approximately 0.0049 ng/well. |
| Storage : | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles. |
IL13 / ALRH Antibody Related Products & Topics
Related Areas:
Proteins:
Cancer>>Angiogenesis>>Cytokines/Chemokines in Angiogenesis>>IL-13
Immunology>>Adaptive Immunity>>B Cell>>IL-13
Immunology>>Adaptive Immunity>>T Cell>>Helper T Cell>>IL-13
Immunology>>Cytokine & Receptor>>Interleukin & Receptor>>Other>>IL-13
Proteins:
| Molecule | Species | Description //For Detailed Info. and Price------CLICK! | Cat. No |
| IL-13/ALRH | Human | IL-13/ALRH/Fc Protein, Recombinant |
10369-H01H |
| IL-13/ALRH | Human | IL-13/ALRH Protein, Recombinant, with Native |
10369-HNAC |
| IL-13/ALRH | Mouse | IL-13 / Interleukin-13 Protein, Recombinant, with Native | 50225-MNAH |
| IL-13/ALRH | Cynomolgus | IL-13/ALRH Protein, Recombinant, with Native |
11057-CNAH |
| IL-13/ALRH | Cynomolgus | IL-13/ALRH Protein, Recombinant |
11057-C07H |
Antibodies:
| Molecule | Application | Description //For Detailed Info. and Price------CLICK! | Cat. No |
| Human IL-13 | ELISA | Mouse Monoclonal Antibody | 10369-MM01 |
| Human IL-13 | WB | Mouse Monoclonal Antibody | 10369-MM02 |
| Human IL-13 | WB, ELISA | IL13 / ALRH Antibody (Antigen Affinity Purified) | 10369-RP02 |
| Human IL-13 | WB, ELISA | IL13 / ALRH Antibody | 10369-R062 |
| Cynomolgus IL-13 | WB | Rabbit Polyclonal Antibody | 11057-RP02 |
Antibodies:
IL13 / ALRH Antibody Background
Interleukin 13 (IL-13) is a single-chain cytokine which belongs to the IL13/IL4 family. In humans, IL13 is secreted by many cell types, but especially by T helper type 2 (Th2) cells. IL13 inhibits the production of pro-inflammatory cytokines and chemokines, and thus down-regulates macrophage activity. Meanwhile, IL-13 synergizes with IL2 in regulating IFN-gamma synthesis. IL-13 binds to a multi-subunit receptor comprising the alpha chain of the IL-4 receptor (IL-4Rα) and at least one of two known IL-13-specific binding chains (IL13 Rα1 and IL13 Rα2), and exerts its effects through signal transducer and activator of transcription 6 (STAT6), like IL-4. Accordingly, IL-13 may be critical in regulating inflammatory and immune responses as a central mediator in various cell types.
References
- Minty, A.et al., 1993, Nature, 362: 248-250.
- Sironi, M. et al., 1994, Blood, 84: 1913-1921.
- Monticelli, S.et al., 2004, J. Biol. Chem. 279: 36210-36218.
- Solymar, D.C. et al., 2002, Immunity. 17: 41-50.
- Skinnider, B.F. et al., 2002, Leuk. Lymphoma. 43: 1203-1210.
