>Rabbit PAb Antibody
>IL-13 / ALRH Antibody (Antigen Affinity Purified)
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IL13 / ALRH Antibody ( Antigen Affinity Purified ) Datasheet
|Order or Inquire for IL13 / ALRH Antibody product||Quality antibodies||Antibody production services|
|Detection limit is 2 ng/lane in WB|
|Detection limit is 0.039 ng/well in ELISA|
IL13 / ALRH Antibody Product Information
Recombinant Human IL13 protein (Catalog#10369-H01H)
|Antibody Type :||Rabbit Polyclonal Antibody ( Antibody Purification Platform )|
|Ig Type :||
|Formulation :||0.2 μm filtered solution in PBS with 5% trehalose|
Produced in rabbits immunized with purified, recombinant Human IL13 / ALRH (rh IL13 / ALRH; Catalog#10369-H01H; AAK53823.1; Gly 21-Asn 132). IL13 / ALRH specific IgG was purified by Human IL13 / ALRH affinity chromatography.
IL13 / ALRH Antibody Usage Guide
Human IL13 / ALRH
|Western blot :||This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Human IL13 in WB. Using a DAB detection system, the detection limit for Human IL13 is approximately 0.5 ng/lane under non-reducing conditions and 2 ng/lane under reducing conditions.|
|Direct ELISA :||This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Human IL13 . The detection limit for Human IL13 is approximately 0.039 ng/well.|
|Storage :||This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
IL13 / ALRH Antibody Related Products & Topics
|Molecule||Species||Description //For Detailed Info. and Price------CLICK!||Cat. No|
|IL-13/ALRH||Human||IL-13/ALRH/Fc Protein, Recombinant||10369-H01H|
|IL-13/ALRH||Human||IL-13/ALRH Protein, Recombinant, with Native||10369-HNAC|
|IL-13/ALRH||Mouse||IL-13 / Interleukin-13 Protein, Recombinant, with Native||50225-MNAH|
|IL-13/ALRH||Cynomolgus||IL-13/ALRH Protein, Recombinant, with Native||11057-CNAH|
|IL-13/ALRH||Cynomolgus||IL-13/ALRH Protein, Recombinant||11057-C07H|
|Molecule||Application||Description //For Detailed Info. and Price------CLICK!||Cat. No|
|Human IL-13||ELISA||Mouse Monoclonal Antibody||10369-MM01|
|Human IL-13||WB||Mouse Monoclonal Antibody||10369-MM02|
|Human IL-13||WB, ELISA||IL13 / ALRH Antibody (Antigen Affinity Purified)||10369-RP02|
|Human IL-13||WB, ELISA||IL13 / ALRH Antibody||10369-R062|
|Cynomolgus IL-13||WB||Rabbit Polyclonal Antibody||11057-RP02|
IL13 / ALRH Antibody Background
Interleukin 13 (IL-13) is a single-chain cytokine which belongs to the IL13/IL4 family. In humans, IL13 is secreted by many cell types, but especially by T helper type 2 (Th2) cells. IL13 inhibits the production of pro-inflammatory cytokines and chemokines, and thus down-regulates macrophage activity. Meanwhile, IL-13 synergizes with IL2 in regulating IFN-gamma synthesis. IL-13 binds to a multi-subunit receptor comprising the alpha chain of the IL-4 receptor (IL-4Rα) and at least one of two known IL-13-specific binding chains (IL13 Rα1 and IL13 Rα2), and exerts its effects through signal transducer and activator of transcription 6 (STAT6), like IL-4. Accordingly, IL-13 may be critical in regulating inflammatory and immune responses as a central mediator in various cell types.
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- Sironi M. et al., 1994, Blood. 84: 1913-21.
- Monticelli S. et al., 2004, J Biol Chem. 279: 36210-8.
- Solymar DC. et al., 2002, Immunity. 17: 41-50.
- Skinnider BF. et al., 2002, Leuk Lymphoma. 43: 1203-10.