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Mouse IL12B / IL-12B Protein (His Tag)
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Mouse IL12B / IL-12B Protein (His Tag) (Cytokine) PDF Download

Catalog   Size (Price) Quantity In Stock Operation
51004-M08H  
YES   
 

Protein Production & Purification Service | Recombinant Cytokines & Growth Factors

Interleukin 12b Protein Datasheet

 

IL12B / IL-12B Protein Price Inquiry ( Available Sizes )

IL12B / IL-12B Protein Product Information

Synonym : IL12B
Protein Construction:

A DNA sequence encoding the mouse IL12B (Met1-Ser335) was expressed with a C-terminal polyhistidine tag.

Source: Mouse
Expression Host: Human Cells

IL12B / IL-12B Protein QC Testing

Purity: > 95% as determined by SDS-PAGE SDS-PAGE:
SDS-PAGE

IL12B / IL-12B protein

Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method
Stability: Samples are stable for up to twelve months from date of receipt at -70℃
Predicted N terminal: Met 23
Molecular Mass:

The recombinant mouse IL12B comprises 324 amino acids and has a predicted molecular mass of 37.2 kDa. The apparent molecular mass of the protein is approximately 47-51 kDa in SDS-PAGE under reducing conditions due to glycosylation.

Formulation: Lyophilized from sterile PBS, pH7.4.
  1. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
  2. Please contact us for any concerns or special requirements.

IL12B / IL-12B Protein Usage Guide

Storage: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

IL12B / IL-12B Protein Related Products & Topics

Related Areas:

Cancer>>Angiogenesis>>Cytokines/Chemokines in Angiogenesis>>IL-12B/IL-12p40

Immunology>>Adaptive Immunity>>T Cell>>Helper T Cell>>IL-12B/IL-12p40

Immunology>>Cytokine & Receptor>>Interleukin & Receptor>>IL-12 Family & Receptor>>IL-12B/IL-12p40

Immunology>>Innate Immunity>>Monocyte/Macrophage>>Macrophage Marker>>IL-12B/IL-12p40

Proteins:

Molecule Species Description //For Detailed Info. and Price------CLICK! Cat. No
IL-12B/IL-12p40 Human IL-12B/IL-12p40/Fc Protein, Recombinant 10052-H02H
IL-12B/IL-12p40 Human IL-12B/IL-12p40 Protein, Recombinant 10052-H08H
IL-12B/IL-12p40 Mouse IL12B / IL-12B Protein, Recombinant 51004-M02H
IL-12B/IL-12p40 Mouse IL12B / IL-12B Protein, Recombinant 51004-M08H

Antibodies:

Molecule Application Description //For Detailed Info. and Price------CLICK! Cat. No
Human
IL-12B/IL-12p40
ELISA Mouse Monoclonal Antibody 10052-MM01
Human
IL-12B/IL-12p40
WB, ELISA Rabbit Monoclonal Antibody 10052-R054
Human
IL-12B/IL-12p40
WB, ELISA Rabbit Polyclonal Antibody (Antigen Affinity Purified) 10052-RP02
Human
IL-12B/IL-12p40
WB, ELISA Rabbit Polyclonal Antibody 10052-RP03

IL12B / IL-12B Protein Description

Interleukin 12 (IL-12), also known as NKSF or CLMF, is a disulfide-linked heterodimeric cytokine composed of a 35kDa subunit P35 and a 40kDa subunit P40, also designated as IL-12A and IL-12B. IL-12 is predominantly produced by macrophages and B lymphocytes and plays an important role in the activities of natural killer cells and T lymphocytes. It is involved in the differentiation and development of Th1 cells, enhancement of natural killer cells’ cytolytic function and mitogenic effects, as well as induction of IFN-gamma during which it can synergize with other IFN-gamma inducers. A large excess of monomeric IL-12B is also secreted by the cells producing IL-12, and exhibits no demonstrable biological activity. Overexpression of IL-12B has been shown to be associated with the pathogenesis of multiple sclerosis.

References

  1. Ling, P. et al., 1995, J. Immunol. 154: 116-27.
  2. Thierfelder, WE. et al., 1996, Nature. 382: 171-4.
  3. Kato, K. et al., 1996, Proc. Natl. Acad. Sci. 93: 9085-89.
  4. Kim, JH. et al., 1997, Clin. Exp. Immunol. 108: 243-50.
 

All IL-12 Proteins

Product nameProduct name
IL12A / NKSF1 ProteinMouse IL12A & IL12B Heterodimer Protein
IL12B / P40 ProteinMouse IL12A & IL12B Heterodimer Protein
IL27 ProteinMouse IL12B / IL-12B Protein
IL27Ra / TCCR / WSX1 ProteinMouse IL6ST / gp130 / CD130 Protein
IL35 / Interleukin-35 ProteinCynomolgus IL23R / IL23 Receptor Protein
IL12B / P40 Protein (His Tag)IL27 / Interleukin-27 Protein (His Tag)
IL6ST / gp130 / CD130 ProteinMouse IL27 / Interleukin-27 Protein (His Tag)
Mouse IL6ST / CD130 ProteinMouse IL12B / IL-12B Protein (His Tag)
IL12A / NKSF1 Protein (His Tag)Rat IL23R / IL23 Receptor Protein
IL27 / Interleukin-27 Protein (His Tag)IL23R / IL23 Receptor Protein
IL12RB1 / IL12RB / CD212 Protein (His Tag)Rat IL12B / IL-12B Protein (His Tag)
Mouse IL12RB2 / IL12R-beta 2 Protein (His Tag)Mouse IL12B / IL-12B Protein
Mouse IL6ST / gp130 / CD130 Protein (His Tag)Mouse IL-23 / IL23A & IL12B Heterodimer Protein (His Tag)
Rat gp130 / IL6ST / CD130 ProteinMarmoset IL12B / IL-12B Protein
Human IL-12 / Interleukin-12 ( IL12A & IL12B Heterodimer ) Protein (His Tag)Cynomolgus IL6ST / gp130 Protein
Human IL-23 / Interleukin-23 ( IL-23A & IL-12B Heterodimer ) Protein (His Tag)Marmoset IL23A & IL12B Heterodimer Protein (His Tag)
Rat gp130 / IL6ST / CD130 Protein (His Tag)Cynomolgus IL6ST / gp130 Protein (His Tag)
Mouse IL12A & IL12B Heterodimer ProteinIL6ST / gp130 / CD130 Protein
Mouse IL12A & IL12B Heterodimer Protein (His Tag)IL12A & IL27B Heterodimer Protein
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"