Anti-IL11RA Antibody

Cat: 50075-R025
Contact us:
All IL11RA Reagents
CRO Services
Product recommended

All IL11RA Reagents
Anti-IL11RA Antibody (Rabbit Monoclonal antibody) General Information
Product name
Anti-IL11RA Antibody
Validated applications
Species reactivity
Reacts with: Mouse
Mouse IL11RA
Recombinant Mouse IL11RA protein (Catalog#50075-M08H)
This antibody was obtained from a rabbit immunized with purified, recombinant Mouse IL11RA (rM IL11RA; Catalog#50075-M08H; NP_001156873.1; Met 1-Gln 367) .
Monoclonal Rabbit IgG Clone #025
Protein A
0.2 μm filtered solution in PBS with 5% trehalose
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-IL11RA Antibody (Rabbit Monoclonal antibody) Validated Applications
Application Dilution Notes
ELISA 1:5000-1:10000  

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-IL11RA Antibody Alternative Names
Anti-AI314697 Antibody;Anti-GP130 Antibody;Anti-Il-11ra Antibody;Anti-Il11ra Antibody;Anti-Il11ra1 Antibody;Anti-Il11ra2 Antibody;Anti-NR1 Antibody;Anti-RP23-167I12.2 Antibody
IL11RA Background Information

Interleukin 11 receptor, alpha subunit (IL11RA/IL-11RA) is a subunit of the interleukin 11 receptor which is a member of the hematopoietic cytokine receptor family. IL11RA/IL-11RA is expressed in a number of cell lines, including the myelogenous leukemia cell line K562, the megakaryocytic leukemia cell line Mo7E, the erythroleukemia cell line TF1, and the osteosarcoma cell lines, MG-63 and Saos-2. It is also expressed in normal and malignant prostate epithelial cell lines. Expression levels are increased in prostate carcinoma. This particular receptor is very similar to ciliary neurotrophic factor, since both contain an extracellular region with a 2-domain structure composed of an immunoglobulin-like domain and a cytokine receptor-like domain. Alternative splicing has been observed at this locus, and three variants encoding two different isoforms have been identified. IL11RA/IL-11RA is a receptor for interleukin-11. The receptor systems for IL6, LIF, OSM, CNTF, IL11 and CT1 can utilize IL6ST for initiating signal transmission. Defects in IL11RA/IL-11RA are a cause of craniosynostosis and dental anomalies (CRSDA). CRSDA is a disorder characterized by craniosynostosis, maxillary hypoplasia, and dental anomalies, including malocclusion, delayed and ectopic tooth eruption, and/or supernumerary teeth. Some patients also display minor digit anomalies, such as syndactyly and/or clinodactyly.

Full Name
interleukin 11 receptor subunit alpha
  • Van Leuven F, et al. (1996) Molecular cloning and characterization of the human interleukin-11 receptor alpha-chain gene, IL11RA, located on chromosome 9p13. Genomics. 31 (1): 65-70.
  • Yoshizaki A, et al. (2006) Expression of interleukin (IL)-11 and IL-11 receptor in human colorectal adenocarcinoma: IL-11 up-regulation of the invasive and proliferative activity of human colorectal carcinoma cells. Int J Oncol. 29 (4): 869-76.
  • Karube K, et al. (2006) Gene expression profile of cytokines and chemokines in microdissected primary Hodgkin and Reed-Sternberg (HRS) cells: high expression of interleukin-11 receptor alpha. Ann Oncol. 17 (1): 110-6.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-IL11RA Antibody Rabbit Polyclonal ELISA 50075-T16
    Anti-IL11RA Antibody Rabbit Polyclonal ELISA 50075-RP01
    Anti-IL11RA Antibody Rabbit Polyclonal WB,ELISA,IP 10252-T52
    Anti-IL11RA Antibody Rabbit Polyclonal WB,ELISA,IHC-P 10252-T56
    info info
    添加购物车成功! 添加购物车失败!