All IL10RB reagents are produced in house and quality controlled, including 11 IL10RB Antibody, 2 IL10RB ELISA, 52 IL10RB Gene, 5 IL10RB Lysate, 5 IL10RB Protein, 3 IL10RB qPCR. All IL10RB reagents are ready to use.
Recombinant IL10RB proteins are expressed by HEK293 Cells with fusion tags as C-His, C-human IgG1-Fc, C-human IgG1-Fc & His.
IL10RBantibodies are validated with different applications, which are ELISA, WB, ELISA(Det), ELISA(Cap).
IL10RBcDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each IL10RB of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.
IL10RBELISA Kit are quality controlled by 8 internation QC standard which guarantee every ELISA Kit with high quality.
Interleukin 10 receptor, beta subunit (IL10RB/IL-10RB) also known as Cytokine receptor family 2 member 4, Interleukin-10 receptor subunit 2, and cytokine receptor family II, member 4, is a subunit for the interleukin-10 receptor. IL10RB/IL-10RB belongs to the cytokine receptor family. It is an accessory chain essential for the active interleukin 10 receptor complex. Coexpression of this and IL10RA proteins has been shown to be required for IL10-induced signal transduction. Defects in IL10RB/IL-10RB are the cause of inflammatory bowel disease type 25 (IBD25). It is a chronic, relapsing inflammation of the gastrointestinal tract with a complex etiology. It is subdivided into Crohn disease and ulcerative colitis phenotypes. Crohn disease may affect any part of the gastrointestinal tract from the mouth to the anus, but most frequently it involves the terminal ileum and colon. Bowel inflammation is transmural and discontinuous; it may contain granulomas or be associated with intestinal or perianal fistulas. In contrast, in ulcerative colitis, the inflammation is continuous and limited to rectal and colonic mucosal layers; fistulas and granulomas are not observed. Both diseases include extraintestinal inflammation of the skin, eyes, or joints.