Anti-IL-9 Antibody

Cat: 11844-RP02
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All IL-9 Reagents
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All IL-9 Reagents
Anti-IL-9 Antibody (Rabbit Polyclonal antibody) General Information
Product name
Anti-IL-9 Antibody
Validated applications
Species reactivity
Reacts with: Human
Human IL-9
Recombinant Human IL-9 protein (Catalog#11844-H08B)
Produced in rabbits immunized with purified, recombinant Human IL-9 (rh IL-9; Catalog#11844-H08B; NP_000581.1; Gln 19-Il4144). IL-9 specific IgG was purified by Human IL-9 affinity chromatography.
Polyclonal Rabbit IgG
Protein A & Antigen Affinity
0.2 μm filtered solution in PBS with 5% trehalose
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-IL-9 Antibody (Rabbit Polyclonal antibody) Validated Applications
Application Dilution Notes
ELISA 0.1-0.2 μg/mL  

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-IL-9 Antibody Alternative Names
Anti-HP40 Antibody;Anti-IL-9 Antibody;Anti-P40 Antibody
IL-9 Background Information

Interleukin 9, also known as IL-9, is a cytokine (cell signalling molecule) belonging to the group of interleukins. IL-9 is a cytokine that acts as a regulator of a variety of hematopoietic cells. This cytokine stimulates cell proliferation and prevents apoptosis. It functions through the interleukin 9 receptor (IL-9R), which activates different signal transducer and activator (STAT) proteins and thus connects this cytokine to various biological processes. Genetic studies on a mouse model of asthma demonstrated that this cytokine is a determining factor in the pathogenesis of bronchial hyperresponsiveness. IL-9 is a key molecule that affects differentiation of TH17 cells and Treg function. IL-9 predominantly produced by TH17 cells, synergizes with TGF-β1 to differentiate naïve CD4+ T cells into TH17 cells, while IL-9 secretion by TH17 cells is regulated by IL-23. Interestingly, IL-9 enhances the suppressive functions of FoxP3+ CD4+ Treg cells in vitro, and absence of IL-9 signaling weakens the suppressive activity of nTregs in vivo, leading to an increase in effector cells and worsening of experimental autoimmune encephalomyelitis. The mechanism of IL-9 effects on TH17 and Tregs is through activation of STAT3 and STAT5 signaling. Our findings highlight a role of IL-9 as a regulator of pathogenic versus protective mechanisms of immune responses.

Full Name
interleukin 9
  • Elyaman W, et al. (2009) IL-9 induces differentiation of TH17 cells and enhances function of FoxP3+ natural regulatory T cells. Proc Natl Acad Sci U S A. 106(31): 12885-90.
  • Dong Q, et al. (1999) IL-9 induces chemokine expression in lung epithelial cells and baseline airway eosinophilia in transgenic mice. Eur J Immunol. 29(7): 2130-9.
  • Kimura Y, et al. (1995) Sharing of the IL-2 receptor gamma chain with the functional IL-9 receptor complex. Int Immunol. 7(1): 115-20.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-IL-9 Antibody Rabbit Polyclonal ELISA 80459-RP01
    Anti-IL-9 Antibody Rabbit Monoclonal ELISA 80459-R030
    Anti-IL-9 Antibody Mouse Monoclonal ELISA 80459-MM03
    Anti-IL-9 Antibody Rabbit Polyclonal ELISA 80459-T16
    Anti-IL-9 Antibody Rabbit Polyclonal WB,IHC-P 100318-T40
    Anti-IL-9 Antibody Rabbit Monoclonal ELISA 11844-R103
    Anti-IL-9 Antibody Rabbit Polyclonal ELISA 11844-RP01
    Anti-IL-9 Antibody Rabbit Polyclonal ELISA 11844-T16
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