|Catalog||Size (Price)||Quantity||In Stock||Operation||Other Information|
Interleukin 8 Protein Datasheet
IL-8 / CXCL8 Protein Price Inquiry ( Available Sizes )
IL-8 / CXCL8 Protein Product Information
|Synonym :||IL8, CXCL8|
A DNA sequence encoding the canine IL8 (P41324) (Ala23-Pro101) was expressed, with a N-terminal Met.
IL-8 / CXCL8 Protein QC Testing
|Purity:||>95% as determined by SDS-PAGE||SDS-PAGE:
IL-8 / CXCL8 protein
|Endotoxin:||Please contact us for more information.|
|Stability:||Samples are stable for up to twelve months from date of receipt at -70℃|
|Predicted N terminal:||Ala 23|
The recombinant canine IL8 comprises 80 amino acids and has a predicted molecular mass of 9.2 kDa. The apparent molecular mass of the protein is approximately 9 kDa in SDS-PAGE under reducing conditions due to glycosylation.
|Formulation:||Lyophilized from sterile PBS 0.5mMTCEP PH7.4.
IL-8 / CXCL8 Protein Usage Guide
|Storage:||Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.|
|Reconstitution:||A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.|
IL-8 / CXCL8 Protein Related Products & Topics
|Molecule||Species||Description //For Detailed Info. and Price------CLICK!||Cat. No|
|IL-8/CXCL8||Human||IL-8/CXCL8/Fc Protein, Recombinant||10098-H01H1|
|IL-8/CXCL8||Human||IL-8/CXCL8/Fc Protein, Recombinant||10098-H01H2|
|IL-8/CXCL8||Human||IL-8/CXCL8 Protein, Recombinant||10098-HNCH1|
|IL-8/CXCL8||Human||IL-8/CXCL8(aa 6-77) Protein, Recombinant||10098-HNCH2|
|IL-8/CXCL8||Canine||IL-8 / CXCL8 Protein, with Native||70009-DNAE|
IL-8 / CXCL8 Protein Description
Interleukin-8 (IL8), also known as CXCL8, is a member of the CXC chemokine family of small (8–10 kDa) proteins, a subfamily of chemokines within the cytokine superfamily. This chemokine is secreted by a variety of cell types including monocyte/macrophages, T cells, neutrophils, fibroblasts, endothelial cells, and various tumor cell lines in response to inflammatory stimuli (IL-1, TNF, LPS, etc). IL8 has the N-terminal tripeptide Glu-Leu-Arg (ELR) motif, which is known to mediate IL8 receptor binding and subsequent signal transduction, such as the TRAF6- NF-κB pathway, and involved in inflammatory and allergic responses. Furthermore, it has been shown that IL8 also plays a vital role in angiogenesis which is important for tumorigenesis, progression and metastasis, and accordingly the expression levels of IL8 correlate with disease progression in several human carcinomas. Multiple N-terminal processed forms for this protein are available, and this purified IL8 (6-77 amino acids) is the most prominent one.
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