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IL-6 Antibody, Rabbit MAb

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Human IL6 Antibody Product Information
Immunogen:Recombinant Human IL-6 Protein (Catalog#10395-HNAE)
Clone ID:057
Ig Type:Rabbit IgG
Concentration:
Endotoxin:
Formulation:0.2 μm filtered solution in PBS with 5% trehalose
Preparation:This antibody was obtained from a rabbit immunized with purified, recombinant Human IL-6 (rh IL-6; Catalog#10395-HNAE; Val 30-Met 212; NP_000591.1).
Human IL6 Antibody Usage Guide
Specificity:Human IL-6
Application:ELISA

ELISA: 0.1-0.2 μg/mL

This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Human IL6. The detection limit for Human IL6 is approximately 0.00245 ng/well.

Storage:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Other IL6 Antibody Products
Reactivity: Human  
Application: B/N  
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10395-mhK23-200
10395-mhK23-500
200 µg 
500 µg 
Add to Cart
Reactivity: Human  
Application: B/N  
  • Slide 1
10395-R508-200
10395-R508-500
200 µg 
500 µg 
Add to Cart
Reactivity: Human  
Application: IHC-P  
  • Slide 1
  • Slide 1
10395-MM10-100
10395-MM10-50
10395-MM10-200
100 µg 
50 µg 
200 µg 
Add to Cart
Reactivity: Human  
Application: ELISA  WB  IP  
  • Slide 1
  • Slide 1
10395-T52-50
10395-T52-100
10395-T52-200
50 µg 
100 µg 
200 µg 
Add to Cart
Reactivity: Human  
Application: ELISA  WB  
  • Slide 1
10395-T48-100
10395-T48-50
10395-T48-200
100 µg 
50 µg 
200 µg 
Add to Cart
Reactivity: Human  
Application: ELISA  
    10395-RP01-100
    10395-RP01-200
    10395-RP01-400
    100 µg 
    200 µg 
     
    Add to Cart
    Reactivity: Human  
    Application: ELISA  
      10395-MM02-50
      10395-MM02-100
      10395-MM02-200
      50 µg 
      100 µg 
      200 µg 
      Add to Cart
      Reactivity: Human  
      Application: ELISA  WB  
      • Slide 1
      10395-RP03-100
      10395-RP03-50
      10395-RP03-200
      100 µg 
      50 µg 
      200 µg 
      Add to Cart
      Reactivity: Human  
      Application: B/N  
        10395-MK23-200
        10395-MK23-500
        200 µg 
        500 µg 
        Add to Cart
        Reactivity: Human  
        Application: ELISA  
          10395-T16-100
          10395-T16-50
          10395-T16-200
          100 µg 
          50 µg 
          200 µg 
          Add to Cart
          Reactivity: Mouse  
          Application: ELISA  WB  
          • Slide 1
          50136-T48-200
          50136-T48-50
          50136-T48-100
          200 µg 
          50 µg 
          100 µg 
          Add to Cart
          Reactivity: Mouse  
          Application: ELISA  
            50136-RP01-400
            50136-RP01-200
            50136-RP01-100
             
            200 µg 
            100 µg 
            Add to Cart
            Reactivity: Rat  
            Application: ELISA  
              80076-R007-50
              80076-R007-100
              50 µg 
              100 µg 
              Add to Cart
              Reactivity: Rat  
              Application: ELISA  
                80076-T16-50
                80076-T16-200
                80076-T16-100
                50 µg 
                200 µg 
                100 µg 
                Add to Cart
                Reactivity: Cynomolgus  
                Application: ELISA  IHC-P  
                • Slide 1
                • Slide 1
                • Slide 1
                • Slide 1
                • Slide 1
                90197-RP02-50
                90197-RP02-100
                90197-RP02-200
                50 µg 
                100 µg 
                200 µg 
                Add to Cart
                Reactivity: Rhesus  
                Application: ELISA  
                  90197-RP01-200
                  90197-RP01-100
                  90197-RP01-400
                  200 µg 
                  100 µg 
                   
                  Add to Cart
                  Reactivity: Sus scrofa (Pig)  
                  Application: ELISA  
                    62006-RP01-100
                    62006-RP01-400
                    62006-RP01-200
                    100 µg 
                     
                    200 µg 
                    Add to Cart
                    Reactivity: Sus scrofa (Pig)  
                    Application: ELISA  
                      62006-T16-200
                      62006-T16-100
                      62006-T16-50
                      200 µg 
                      100 µg 
                      50 µg 
                      Add to Cart
                      IL6/IL-6/Interleukin-6 Background

                      Interleukin-6 (IL-6) is a multifunctional α-helical cytokine that regulates cell growth and differentiation of various tissues, which is known particularly for its role in the immune response and acute phase reactions. IL-6 protein is secreted by a variety of cell types including T cells and macrophages as phosphorylated and variably glycosylated molecule. It exerts actions through the its heterodimeric receptor composed of IL-6R that lacks the tyrosine/kinase domain and binds IL-6 with low affinity, and ubiquitously expressed glycoprotein 130 (gp130) that binds the IL-6. IL-6R complex with high affinity and thus transduces signals. IL-6 is also involved in hematopoiesis, bone metabolism, and cancer progression, and has been defined an essential role in directing transition from innate to acquired immunity.

                      Human IL6/IL-6/Interleukin-6 References
                    • Heinrich PC. et al. (2003). Principles of interleukin-6-type cytokine signalling and its regulation. Biochem J. 374: 1-20.
                    • Rose-John S, et al. (2007) The IL-6/sIL-6R complex as a novel target for therapeutic approaches. Expert Opin Ther Targets. 11(5): 613-24.
                    • Dinh W, et al. (2009) Elevated plasma levels of TNF-alpha and interleukin-6 in patients with diastolic dysfunction and glucose metabolism disorders. Cardiovasc Diabetol. 8:58.
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                      Catalog: 10395-R057-50
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                      100 µg
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                      All information of our products is subject to change without notice. Please refer to COA enclosed in shipped package for the newest information.
                      Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"