Anti-IL4R Antibody

Cat: 10402-MM01
Contact us:
215-583-7898
order@sinobiological.com
Distributors
All IL4R Reagents
CRO Services
Product recommended

All IL4R Reagents
Anti-IL4R Antibody (Mouse Monoclonal antibody) General Information
Product name
Anti-IL4R Antibody
Validated applications
ELISA
Species reactivity
Reacts with: Human
Specificity
Human IL4R
No cross-reactivity with Human IL13RA1 / CT19 / CD213a1 and Human cell lysate (293 cell line) in ELISA.
Immunogen
Recombinant Human IL4R protein (Catalog#10402-H08H)
Preparation
This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human IL4R (rh IL4R; Catalog#10402-H08H; NP_000409.1; Met 1-His 232). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
Source
Monoclonal Mouse IgG1 Clone #7E10C7
Purification
Protein A
Formulation
0.2 μm filtered solution in PBS
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-IL4R Antibody (Mouse Monoclonal antibody) Validated Applications
Application Dilution Notes
ELISA 1:1000-1:2000  

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-IL4R Antibody Alternative Names
Anti-CD124 Antibody;Anti-IL-4RA Antibody;Anti-IL4R Antibody;Anti-IL4RA Antibody
IL4R Background Information

The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD124, also known as interleukin 4 receptor (IL4R), is a typeⅠ transmembrane protein that can regulate IgE antibody production in B cells through binding to interleukin 4 and interleukin 13 and promote differentiation of Th2 cells through binding to interleukin 4. The membrane-bound form of CD124 can be hydrolyzed to soluble form which can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells.

Full Name
interleukin 4 receptor
References
  • Zola H, et al. (2007) CD molecules 2006-human cell differentiation molecules. J Immunol Methods. 318 (1-2): 1-5.
  • Ho IC, et al. (2009) GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation. Nat Rev Immunol. 9 (2): 125-35.
  • Matesanz-Isabel J, et al. (2011) New B-cell CD molecules. Immunology Letters.134 (2): 104-12.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-IL4R Antibody Rabbit Polyclonal ELISA 80198-T16
    Anti-IL4R Antibody Rabbit Monoclonal ELISA 80198-R002
    Anti-IL4R Antibody Rabbit Polyclonal ELISA 80198-RP01
    Anti-IL4R Antibody Rabbit Polyclonal ELISA 51180-T16
    Anti-IL4R Antibody Rabbit Monoclonal ELISA 51180-R074
    Anti-IL4R Antibody Rabbit Monoclonal FCM 10402-R209
    Anti-IL4R Antibody (PE) Rabbit Monoclonal FCM 10402-R209-P
    IL-4R / CD124 Neutralizing Antibody Rabbit Monoclonal Neutralization 10402-R401
    Anti-IL4R Antibody Rabbit Polyclonal ELISA 10402-RP02
    Anti-IL4R Antibody Rabbit Monoclonal ELISA 10402-R102
    IL-4R / CD124 Neutralizing Antibody Rabbit Monoclonal Neutralization 10402-R001
    Anti-IL4R Antibody (APC) Rabbit Monoclonal FCM 10402-R209-A
    Anti-IL4R Antibody Rabbit Polyclonal ELISA 10402-RP01
    info info
    添加购物车成功! 添加购物车失败!