All IL-33 reagents are produced in house and quality controlled, including 15 IL-33 Antibody, 53 IL-33 Gene, 2 IL-33 Protein, 3 IL-33 qPCR. All IL-33 reagents are ready to use.
Recombinant IL-33 proteins are expressed by E. coli with fusion tags as Native.
IL-33antibodies are validated with different applications, which are FCM, ELISA, WB, IHC-P, ICC/IF, IF.
IL-33cDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each IL-33 of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.
Interleukin 33 (IL-33), also known as DVS27 or NF-HEV (Nuclear Factor from High Endothelial enules), is a proinflammatory protein and a chromatin-associated cytokine of the IL-1 family with high sequence and structural similarity to IL-1 and IL-18. IL-33 protein is expressed highly and rather selectively by high endothelial venule endothelial cells (HEVECs) in human tonsils, Peyers's patches, and lymph nodes. IL-33 protein has transcriptional regulatory properties, and the researches suggested that IL-33 is a dual-function protein that might act both as a cytokine and as an intracellular nuclear factor. As a type 2 cytokines, IL-33 protein also play a pivotal role in helminthic infection and allergic disorders.