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IL-33 Antibody (FITC), Mouse MAb

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Human IL33 Antibody Product Information
Immunogen:Recombinant Human IL-33 protein (Catalog#10368-HNAE)
Clone ID:03
Ig Type:Mouse IgG2b
Concentration:10 μl/Test, 0.1 mg/ml
Formulation:Aqueous solution containing 0.5% BSA and 0.09% sodium azide
Preparation:This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human IL-33 (rh IL-33; Catalog#10368-HNAE; NP_254274.1; Ser 112-Thr 270) and conjugated with FITC under optimum conditions, the unreacted FITC was removed.
Human IL33 Antibody Usage Guide
Specificity:Human IL-33
No cross-reactivity in ELISA with
Human cell lysate (293 cell line)
Storage:This antibody is stable for 12 months from date of receipt when stored at 2℃-8℃. Protected from prolonged exposure to light. Do not freeze !
Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.
Human IL33 Antibody FC Application Image
IL-33 Antibody (FITC), Mouse MAb, Flow cytometric
[Click to enlarge image]
Flow cytometric analysis of Human IL-33 on HUVEC cells. HUVEC cells were treated according to manufacturer’s manual (BD Pharmingen™ Cat. No. 554714), and stained with FITC Mouse anti-IL-33 (Bold line hisgram).
Other IL33 Antibody Products
IL-33 Background

Interleukin 33 (IL-33), also known as DVS27 or NF-HEV (Nuclear Factor from High Endothelial enules), is a proinflammatory protein and a chromatin-associated cytokine of the IL-1 family with high sequence and structural similarity to IL-1 and IL-18. IL-33 protein is expressed highly and rather selectively by high endothelial venule endothelial cells (HEVECs) in human tonsils, Peyers's patches, and lymph nodes. IL-33 protein has transcriptional regulatory properties, and the researches suggested that IL-33 is a dual-function protein that might act both as a cytokine and as an intracellular nuclear factor. As a type 2 cytokines, IL-33 protein also play a pivotal role in helminthic infection and allergic disorders.

Human IL-33 References
  • Iikura M, et al. (2007) IL-33 can promote survival, adhesion and cytokine production in human mast cells. Lab Invest. 87(10): 971-8.
  • Lamkanfi M, et al. (2009) IL-33 raises alarm. Immunity. 31(1): 5-7.
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