Anti-IL-32 Antibody

Cat: 11064-RP01
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All IL-32 Reagents
Anti-IL-32 Antibody (Rabbit Polyclonal antibody) General Information
Product name
Anti-IL-32 Antibody
Validated applications
Species reactivity
Reacts with: Human
Human IL-32
Human cell-derived rhIL32-alpha (Catalog#11064-H08H)
Produced in rabbits immunized with purified, recombinant Human IL32 isoform alpha (rhIL32 alpha; Catalog#11064-H08H; NP_001012651.1; Met 1-Lys 131). Total IgG was purified by Protein A affinity chromatography.
Polyclonal Rabbit IgG
Protein A
0.2 μm filtered solution in PBS with 5% trehalose
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-IL-32 Antibody (Rabbit Polyclonal antibody) Validated Applications
Application Dilution Notes
ELISA 1:1000-1:2000  

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-IL-32 Antibody Alternative Names
Anti-IL-32alpha Antibody;Anti-IL-32beta Antibody;Anti-IL-32delta Antibody;Anti-IL-32gamma Antibody;Anti-IL32 Antibody;Anti-NK4 Antibody;Anti-TAIF Antibody;Anti-TAIFa Antibody;Anti-TAIFb Antibody;Anti-TAIFc Antibody;Anti-TAIFd Antibody
IL-32 Background Information

IL-32 is a recently discovered cytokine that induces various proinflammatory cytokines (TNF-alpha, IL-1beta, IL-6) and chemokines in both human and mouse cells through the NF-kappaB and p38 MAPK inflammatory signal pathways. It is regulated robustly by other major proinflammatory cytokines, and is crucial to inflammation and immune responses. Four of the IL-32 isoforms (alpha, beta, gamma and delta) are the most representative IL-32 transcripts, and gamma isoform of IL-32 is the most active, although all isoforms are biologically active. IL-32, a cytokine produced mainly by T, natural killer, and epithelial cells induces significant amounts of TNFalpha and MIP-2 and increases the production of both cytokines in a dose-dependent manner. IL-32 has been implicated in inflammatory disorders, mycobacterium tuberculosis infections, inflammatory bowel disease, and influenza A virus infection, as well as in some autoimmune diseases, such as rheumatoid arthritis, ulcerative colitis and in human stomach cancer, human lung cancer and breast cancer tissues. Thus, IL-32 expression might be valuable as a biomarker for cancer.

Full Name
interleukin 32
  • Felaco P, et al. (2009) IL-32: a newly-discovered proinflammatory cytokine. J Biol Regul Homeost Agents. 23(3): 141-7.
  • Kobayashi H, et al. (2009) Molecular characterization of IL-32 in human endothelial cells. Cytokine. 46(3): 351-8.
  • Meyer N, et al. (2010) IL-32 is expressed by human primary keratinocytes and modulates keratinocyte apoptosis in atopic dermatitis. J Allergy Clin Immunol. 125(4): 858-865.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-IL-32 Antibody Rabbit Monoclonal ELISA,ELISA(Det) 11064-R403
    Anti-IL-32 Antibody Mouse Monoclonal WB 11064-MM12
    Anti-IL-32 Antibody Rabbit Polyclonal ELISA 11064-T16
    Anti-IL-32 Antibody Rabbit Polyclonal WB 100285-T32
    Anti-IL-32 Antibody Rabbit Monoclonal ELISA 11064-R030
    Anti-IL-32 Antibody Rabbit Monoclonal ELISA(Cap) 11064-R034
    Anti-IL-32 Antibody Rabbit Polyclonal WB,ELISA 11064-T48
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