IL24 (Protein|Antibody|cDNA Clone|ELISA Kit)

All IL24 reagents are produced in house and quality controlled, including 2 IL24 Antibody, 39 IL24 Gene, 2 IL24 Lysate, 2 IL24 Protein, 3 IL24 qPCR. All IL24 reagents are ready to use.

Recombinant IL24 proteins are expressed by HEK293 Cells with fusion tags as C-mouse IgG1-Fc, C-His.

IL24 antibodies are validated with different applications, which are ELISA.

IL24 cDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each IL24 of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.

IL24 Protein (2)

Species

IL24 Protein, Human, Recombinant (Fc Tag)

12265-H05H

Expression host: HEK293 Cells

Human IL-24/MDA-7 Protein 18804

IL24 Protein, Human, Recombinant (His Tag)

12265-H08H

Expression host: HEK293 Cells

Human IL-24/MDA-7 Protein 10027
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IL24 Antibody (2)

Application
Clonality
Host

Anti-IL24 Antibody

12265-R101

Specificity: Human

Application: ELISA

Clonality: MAb

Anti-IL24 Antibody

12265-T16

Specificity: Human

Application: ELISA

Clonality: PAb

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IL24 cDNA Clone (39)

Human
Mouse
Rat

IL24 qPCR Primer (3)

IL24 Lysate (2)

Interleukin-24 (IL-24) also known as Melanoma differentiation-associated gene 7 protein (MDA-7) is a member of the IL1 family of cytokines. IL-24/MDA-7/IL24 can induce apoptosis selectively in various cancer cells. Overexpression of IL-24 leads to elevated expression of several GADD family genes, which correlates with the induction of apoptosis. The phosphorylation of mitogen-activated protein kinase 14 (MAPK7/P38), and heat shock 27kDa protein 1 (HSPB2/HSP27) are found to be induced by this gene in melanoma cells, but not in normal immortal melanocytes. Human IL-24/MDA-7/IL24 is secreted by activated peripheral blood mononuclear cells and is the ligand for two heterodimeric receptors, IL-22R1/IL-2R2 and IL-2R1/IL-2R2. Northern blot analysis revealed IL-24/MDA-7/IL24 expression in human tissues associated with the immune system such as spleen, thymus, peripheral blood leukocytes and normal melanocytes. IL-24/MDA-7/IL24 binding to either its endogenous receptors on human keratinocytes or to ectopically expressed receptors on baby hamster kidney cells leads to activation of the signal transducers and activators of transcription.
Protein
Antibody
Gene
qPCR
Lysate
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