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Product Catalog
> IL-22BP Protein & Antibody (IL-22RA2) IL-22BP Protein & Antibody (IL-22RA2)
Interleukin 22-binding protein (Interleukin-22 Receptor, Alpha 2)
IL-22BP Products
IL-22BP Protein, Recombinant
| Molecule | Species | Description //For Detailed Info. and Price------CLICK! | Cat. No |
| IL-22BP/IL-22RA2 | Human | IL-22BP/IL-22RA2 Protein, Recombinant | 11025-H08H |
| IL-22BP/IL-22RA2 | Human | IL-22BP/IL-22RA2/Fc Protein, Recombinant | 11025-H03H |
IL-22BP Antibody
| Molecule | Application | Description //For Detailed Info. and Price------CLICK! | Cat. No |
| Human IL-22BP/IL-22RA2 |
ELISA | Mouse Monoclonal Antibody | 11025-MM05 |
| Human IL-22BP/IL-22RA2 |
WB | Mouse Monoclonal Antibody | 11025-MM06 |
| Human IL-22BP/IL-22RA2 |
WB | Rabbit Monoclonal Antibody | 11025-R002 |
| Human IL-22BP/IL-22RA2 |
ELISA | IL-22BP/IL-22RA2 Antibody, Rabbit MAb | 11025-R028 |
| Human IL-22BP/IL-22RA2 |
WB, ELISA | Rabbit Polyclonal Antibody | 11025-RP01 |
| Human IL-22BP/IL-22RA2 |
WB, ELISA | Rabbit Polyclonal Antibody (Antigen Affinity Purified) | 11025-RP02 |
IL-22BP cDNA Clone
| Molecule | Species | Description //For Detailed Info. and Price------CLICK! | Cat. No |
| IL-22BP/IL-22RA2 | Human | Homo sapiens IL-22BP/IL-22RA2 cDNA Clone(NM_181309.1) | HG11025-M |
| IL-22BP/IL-22RA2 | Human | Homo sapiens IL-22BP/IL-22RA2 cDNA Clone(NM_052962.2) | HG10781-M |
| IL-22BP/IL-22RA2 | Mouse | Mus musculus IL-22BP/IL-22RA2 cDNA Clone | MG50102-M |
| IL-22BP/IL-22RA2 | Rat | Rat IL-22BP/IL-22RA2 cDNA Clone | RG80203-G |
IL-22BP Related Areas
Immunology>>Adaptive Immunity>>T Cell>>Helper T Cell>>IL-22BP/IL-22RA2
Immunology>>Cytokine & Receptor>>Interleukin & Receptor>>IL-10/Interferon Family>>IL-22BP/IL-22RA2
IL-22BP Alternative Names
IL-22BP, IL22RA2, CRF2-10, CRF2-S1, CRF2X, MGC150509, MGC150510 [Homo sapiens]
Il-22bp, Il22ra2, CRF2-10, CRF2-s1, CRF2X [Mus musculus]
IL-22BP Background
Interleukin-22 receptor subunit alpha-2 (IL-22RA2), also known as interleukin-22-binding protein (IL-22BP), is a subunit of the receptor for interleukin 22. IL-22BP belongs to the type I I cytokine receptor family and contains 3 fibronectin type-III domains. IL-22BP/IL-22RA2 is expressed in a range of tissues, including those in the digestive, female reproductive, and immune systems. It is expressed in placenta, spleen, breast, skin and lung. It is also detected in intestinal tract, testis, brain, heart and thymus. The dominant cell types expressing IL-22BP/IL-22RA2 were mononuclear cells and epithelium. IL-22BP/IL-22RA2 may play an important role as an IL-22 antagonist in the regulation of inflammatory responses. Interleukin-22 (IL-22) is a member of IL-10 family. It is produced by T cells and induces the production of acute-phase reactants. IL-22 plays important roles in immune response through activation of the STAT 3 signal transduction pathway. Two types of IL-22-binding receptor have been discovered, a membrane-bound receptor and a soluble receptor.
IL-22BP Related Studies
- Whittington HA, et al. (2004) Interleukin-22: a potential immunomodulatory molecule in the lung. Am J Respir Cell Mol Biol. 31(2): 220-6.
- Dumoutier L, et al. (2001) Cloning and characterization of IL-22 binding protein, a natural antagonist of IL-10-related T cell-derived inducible factor/IL-22. J Immunol. 166(12): 7090-5.
- Wei CC, et al. (2003) Cloning and characterization of mouse IL-22 binding protein. Genes Immun. 4(3): 204-11.
