IL2 (Protein|Antibody|cDNA Clone|ELISA Kit)

All IL2 reagents are produced in house and quality controlled, including 16 IL2 Antibody, 78 IL2 Gene, 4 IL2 Protein, 3 IL2 qPCR. All IL2 reagents are ready to use.

Recombinant IL2 proteins are expressed by E. coli, Yeast with fusion tags as Native.

IL2 antibodies are validated with different applications, which are ELISA, WB, IHC-P, FCM.

IL2 cDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each IL2 of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.

IL2 Protein (4)

Species

IL2 Protein, Mouse, Recombinant

51061-MNAE

Expression host: E. coli

Mouse IL2/IL-2/Interleukin-2 Protein 12048

IL2 Protein, Canine, Recombinant (147 Cys/Ser)

70014-DNAE

Expression host: E. coli

Canine IL2/IL-2/Interleukin-2 Protein 12225

IL2 Protein, Rat, Recombinant

80075-RNAE

Expression host: E. coli

Rat IL2/IL-2/Interleukin-2 Protein 12368

IL2 Protein, Human, Recombinant (L35M, L36S, C142A)

11848-HNAY1

Expression host: Yeast

Human IL2/IL-2/Interleukin-2 Protein 9863
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IL2 Antibody (16)

Application Clonality
Host

Anti-IL2 Antibody

51061-R257

Specificity: Mouse

Application: ELISA

Clonality: MAb

Anti-IL2 Antibody

51061-RP01

Specificity: Mouse

Application: ELISA

Clonality: PAb

Anti-IL2 Antibody

51061-T16

Specificity: Mouse

Application: ELISA

Clonality: PAb

Anti-IL2 Antibody (PE)

80075-MM06-P

Specificity: Rat

Application: FCM

Clonality: MAb

Rat IL2/IL-2/Interleukin-2 Flow Cytometry (FC) 18502

Anti-IL2 Antibody

11848-R062

Specificity: Human

Application: ELISA

Clonality: MAb

Anti-IL2 Antibody

80075-MM10

Specificity: Rat

Application: IHC-P

Clonality: MAb

Rat IL2/IL-2/Interleukin-2 Immunohistochemistry(IHC) 3113

Anti-IL2 Antibody

11848-T16

Specificity: Human

Application: ELISA

Clonality: PAb

Anti-IL2 Antibody

11848-R365

Specificity: Human

Application: ELISA

Clonality: MAb

Anti-IL2 Antibody

70014-R001

Specificity: Canine

Application: ELISA

Clonality: MAb

Anti-IL2 Antibody

51061-T48

Specificity: Mouse

Application: WB,ELISA

Clonality: PAb

Mouse IL2/IL-2/Interleukin-2 Western blot (WB) 6793

Anti-IL2 Antibody

11848-MM03

Specificity: Human

Application: ELISA

Clonality: MAb

Anti-IL2 Antibody

11848-RP01

Specificity: Human

Application: ELISA

Clonality: PAb

Anti-IL2 Antibody

80075-T16

Specificity: Rat

Application: ELISA

Clonality: PAb

Anti-IL2 Antibody

70014-RP01

Specificity: Canine

Application: ELISA

Clonality: PAb

Anti-IL2 Antibody

70014-T48

Specificity: Canine

Application: WB,ELISA

Clonality: PAb

Canine IL2/IL-2/Interleukin-2 Western blot (WB) 13726

Anti-IL2 Antibody

11848-R011

Application: ELISA

Clonality: MAb

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IL2 cDNA Clone (78)

Mouse
Rat
Human
Canine
Rabbit
Rhesus

IL2 qPCR Primer (3)

Interleukin-2, also known as T-cell growth factor, TCGF, Aldesleukin and IL2, is a secreted protein which belongs to the IL-2 family. Interleukin-2 / IL-2 was the first interleukin molecule to be discovered. Interleukin-2 / IL-2 molecule was first purified to homogeneity by immunoaffinity chromatography by Kendall Smith and his team at Dartmouth Medical School. Interleukin-2 / IL-2 was also the first cytokine shown to mediate its effects via a specific IL-2 receptor, and it was also the first interleukin to be cloned and expressed from a complementary DNA (cDNA) library. Interleukin-2 / IL-2 was designated number 2 because Smith's data at the time indicated that IL-1, produced by macrophages, facilitates IL-2 production by T lymphocytes (T cells).
Interleukin-2 / IL-2 is produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Interleukin-2 / IL-2 is normally produced by the body during an immune response. When environmental substances (molecules or microbes) gain access to the body, these substances (termed antigens) are recognized as foreign by antigen receptors that are expressed on the surface of lymphocytes. Antigen binding to the T cell receptor (TCR) stimulates the secretion of Interleukin-2 / IL-2, and the expression of IL-2 receptors IL-2R. The IL-2 / IL-2R interaction then stimulates the growth, differentiation and survival of antigen-selected cytotoxic T cells via the activation of the expression of specific genes. Interleukin-2 / IL-2 can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells. The World Reference Standard for Interleukin-2 / IL-2 is produced by the National Institute of Biological Standards and Control in the UK. A recombinant form of Interleukin-2 / IL-2 for clinical use is manufactured by Chiron Corporation with the brand name Proleukin. It has been approved by the Food and Drug Administration (FDA) for the treatment of cancers (malignant melanoma, renal cell cancer), and is in clinical trials for the treatment of chronic viral infections, and as a booster (adjuvant) for vaccines. The use of Interleukin-2 / IL-2 in HIV therapy has been found to be ineffective.Immune Checkpoint   Immunotherapy   Cancer Immunotherapy   Targeted Therapy
Protein
Antibody
Gene
qPCR
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