IL1RAP (Protein|Antibody|cDNA Clone|ELISA Kit)

All IL1RAP reagents are produced in house and quality controlled, including 8 IL1RAP Antibody, 28 IL1RAP Gene, 4 IL1RAP Lysate, 4 IL1RAP Protein, 2 IL1RAP qPCR. All IL1RAP reagents are ready to use.

Recombinant IL1RAP proteins are expressed by HEK293 Cells with fusion tags as C-His, C-human IgG1-Fc, C-human IgG1-Fc & His.

IL1RAP antibodies are validated with different applications, which are ELISA, WB, FCM.

IL1RAP cDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each IL1RAP of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.

IL1RAP Protein (4)

Species

IL1RAP Protein, Human, Recombinant (His & Fc Tag)

10121-H03H

Expression host: HEK293 Cells

Human IL-1RAcP/IL-1R3 Protein 8419

IL1RAP Protein, Human, Recombinant (His Tag)

10121-H08H

Expression host: HEK293 Cells

Human IL-1RAcP/IL-1R3 Protein 8420

IL1RAP Protein, Mouse, Recombinant (His Tag)

52657-M08H

Expression host: HEK293 Cells

Mouse IL-1RAcP/IL-1R3 Protein 6369

IL1RAP Protein, Mouse, Recombinant (Fc Tag)

52657-M02H

Expression host: HEK293 Cells

Mouse IL-1RAcP/IL-1R3 Protein 6368
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IL1RAP Antibody (8)

Application Clonality
Host

Anti-IL1RAP Antibody

10121-MM05

Specificity: Human

Application: ELISA,FCM

Clonality: MAb

Human IL-1RAcP/IL-1R3 Flow Cytometry (FC) 5131

Anti-IL1RAP Antibody (FITC)

10121-MM05-F

Specificity: Human

Application: FCM

Clonality: MAb

Human IL-1RAcP/IL-1R3 Flow Cytometry (FC) 5132

Anti-IL1RAP Antibody

10121-RP01

Specificity: Human

Application: ELISA

Clonality: PAb

Anti-IL1RAP Antibody (APC)

10121-MM05-A

Specificity: Human

Application: FCM

Clonality: MAb

Human IL-1RAcP/IL-1R3 Flow Cytometry (FC) 5132

Anti-IL1RAP Antibody

10121-RP02

Specificity: Human

Application: ELISA

Clonality: PAb

Anti-IL1RAP Antibody

10121-MM04

Specificity: Human

Application: ELISA

Clonality: MAb

Anti-IL1RAP Antibody

10121-T48

Specificity: Human

Application: WB,ELISA

Clonality: PAb

Human IL-1RAcP/IL-1R3 Western blot (WB) 13126

Anti-IL1RAP Antibody (PE)

10121-MM05-P

Specificity: Human

Application: FCM

Clonality: MAb

Human IL-1RAcP/IL-1R3 Flow Cytometry (FC) 5132
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IL1RAP cDNA Clone (28)

Rat
Human
Mouse

IL1RAP qPCR Primer (2)

IL1RAP Lysate (4)

Interleukin-1 receptor accessory protein (IL-1RAcP) also known as Interleukin-1 receptor member 3 (IL-1R3) is a a cytokine receptor which binds interleukin 1. The IL-1 receptor accessory protein (IL1RAP) is a transmembrane protein that interacts with IL-1R and is required for IL-1 signal transduction. Interleukin 1 induces synthesis of acute phase and proinflammatory proteins during infection, tissue damage, or stress, by forming a complex at the cell membrane with an interleukin 1 receptor and an accessory protein. IL-1RAcP/IL-1R3 is a necessary part of the interleukin 1 receptor complex which initiates signalling events that result in the activation of interleukin 1-responsive genes. Alternative splicing of this gene results in two transcript variants encoding two different isoforms, one membrane-bound and one soluble. The ratio of soluble to membrane-bound forms increases during acute-phase induction or stress. IL-1RAcP/IL-1R3 mediates interleukin-1-dependent activation of NF-kappa-B. Isoform 1 is part of the membrane-bound form of the IL-1 receptor. Signaling involves formation of a ternary complex containing IL1R1, TOLLIP, MYD88, and IRAK1 or IRAK2. Isoform 2 modulates the response to interleukins by associating with soluble IL1R1 and enhancing interleukin-binding to the decoy receptor.
Protein
Antibody
Gene
qPCR
Lysate
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