IL-1R9 Protein (IL1RAPL2 Protein)

Interleukin-1 Receptor 9 (Interleukin 1 Receptor Accessory Protein-Like 2)

IL-1R9 Products

IL-1R9 Protein, Recombinant

Molecule	Species	Description //For Detailed Info. and Price------CLICK!	Cat. No
IL-1R9	Human	IL-1RAPL2/IL-1R9/Fc Protein, Recombinant	10156-H02H
IL-1R9	Human	IL-1RAPL2/IL-1R9 Protein, Recombinant	10156-H08H

IL-1R9 Antibody

Molecule	Application	Description	Cat. No
Human IL-1R9	WB,Elisa	Rabbit Polyclonal Antibody (Antigen Affinity Purified)	10156-RP02

IL-1R9 cDNA Clone

Molecule	Species	Description //For Detailed Info. and Price------CLICK!	Cat. No
IL-1R9/IL1RAPL2	Human	Homo sapiens IL1RAPL2/IL-1R9 cDNA Clone(NM_017416.1)	HG10156-M

IL-1R9 Related Areas

Immunology>>Cytokine & Receptor>>Interleukin & Receptor>>IL-1 superfamily and IL-1R/TLR family >>IL-1R9/IL1RAPL2

IL-1R9 Alternative Names

IL-1R9, ILRAPL2, IL1R9, IL1RAPL-2, TIGIRR-1 [Homo sapiens]

IL-1R9 Background

X-linked interleukin-1 receptor accessory protein-like 2 (IL1RAPL2) or Interleukin-1 receptor 9 (IL-1R9) is a member of the interleukin 1 receptor family. This protein is similar to the interleukin 1 accessory proteins. IL-1R9/IL1RAPL2 shows restricted expression in fetal brain and is highly homologous to IL1RAPL, which is reportedly involved in nonsyndromic X-linked mental retardation. IL-1R9/IL1RAPL2 is highly homologous to IL-1R8. Both forms have no known ligands and receptor are found in the fetal brain. IL-1R9/IL1RAPL2 may function as a negative receptor. Both IL1RAPL1 and IL1RAPL2 have novel C-terminal sequences not present in other related proteins. IL-1R9/IL1RAPL2 may be strong candidates for X-linked non-syndromic mental retardation loci, and that molecules resembling IL-1 and IL-18 play a role in the development or function of the central nervous system.

IL-1R9 Related Studies

1. Jin H, et al. (2000) Two novel members of the interleukin-1 receptor gene family, one deleted in Xp22.1-Xp21.3 mental retardation. Eur J Hum Genet. 8(2): 87-94.
2. Sana TR, et al. (2000) Computational identification, cloning, and characterization of IL-1R9, a novel interleukin-1 receptor-like gene encoded over an unusually large interval of human chromosome Xq22.2-q22.3. Genomics. 69(2): 252-62.
3. Gambino F, et al. (2007) IL1-receptor accessory protein-like 1 (IL1RAPL1), a protein involved in cognitive functions, regulates N-type Ca²⁺-channel and neurite elongation. Proc Natl Acad Sci. 104(21): 9063-8.