Anti-IL-1 R9 Antibody

Cat: 10156-RP02
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Anti-IL-1 R9 Antibody (Rabbit Polyclonal antibody) General Information
Product name
Anti-IL-1 R9 Antibody
Validated applications
ELISA
Species reactivity
Reacts with: Human
Specificity
Human IL-1 R9
Immunogen
Recombinant Human IL-1R9 / IL1RAPL2 protein (Catalog#10156-H08H)
Preparation
Produced in rabbits immunized with purified, recombinant Human IL-1R9 / IL1RAPL2 (rh IL-1R9 / IL1RAPL2; Catalog#10156-H08H; NP_059112.1; Met 1-Glu 356). IL-1R9 / IL1RAPL2 specific IgG was purified by Human IL-1R9 / IL1RAPL2 affinity chromatography.
Source
Polyclonal Rabbit IgG
Purification
Protein A & Antigen Affinity
Formulation
0.2 μm filtered solution in PBS with 5% trehalose
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-IL-1 R9 Antibody (Rabbit Polyclonal antibody) Validated Applications
Application Dilution Notes
ELISA 1:5000-1:10000  

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-IL-1 R9 Antibody Alternative Names
Anti-IL-1R9 Antibody;Anti-IL1R9 Antibody;Anti-IL1RAPL-2 Antibody;Anti-TIGIRR-1 Antibody
IL-1 R9 Background Information

X-linked interleukin-1 receptor accessory protein-like 2 (IL1RAPL2) or Interleukin-1 receptor 9 (IL-1R9) is a member of the interleukin 1 receptor family. This protein is similar to the interleukin 1 accessory proteins. IL-1R9/IL1RAPL2 shows restricted expression in fetal brain and is highly homologous to IL1RAPL, which is reportedly involved in nonsyndromic X-linked mental retardation. IL-1R9/IL1RAPL2 is highly homologous to IL-1R8. Both forms have no known ligands and receptor are found in the fetal brain. IL-1R9/IL1RAPL2 may function as a negative receptor. Both IL1RAPL1 and IL1RAPL2 have novel C-terminal sequences not present in other related proteins. IL-1R9/IL1RAPL2 may be strong candidates for X-linked non-syndromic mental retardation loci, and that molecules resembling IL-1 and IL-18 play a role in the development or function of the central nervous system.

Full Name
interleukin 1 receptor accessory protein-like 2
References
  • Jin H, et al. (2000) Two novel members of the interleukin-1 receptor gene family, one deleted in Xp22.1-Xp21.3 mental retardation. Eur J Hum Genet. 8(2): 87-94.
  • Sana TR, et al. (2000) Computational identification, cloning, and characterization of IL-1R9, a novel interleukin-1 receptor-like gene encoded over an unusually large interval of human chromosome Xq22.2-q22.3. Genomics. 69(2): 252-62.
  • Gambino F, et al. (2007) IL1-receptor accessory protein-like 1 (IL1RAPL1), a protein involved in cognitive functions, regulates N-type Ca2+-channel and neurite elongation. Proc Natl Acad Sci. 104(21): 9063-8.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-IL-1 R9 Antibody Mouse Monoclonal ELISA 10156-MM02
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