IL36RN (Protein|Antibody|cDNA Clone|ELISA Kit)

All IL36RN reagents are produced in house and quality controlled, including 8 IL36RN Antibody, 26 IL36RN Gene, 2 IL36RN Protein, 2 IL36RN qPCR. All IL36RN reagents are ready to use.

Recombinant IL36RN proteins are expressed by E. coli with fusion tags as Native.

IL36RN antibodies are validated with different applications, which are ELISA, IHC-P.

IL36RN cDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each IL36RN of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.

IL36RN Protein (2)

Species

IL36RN Protein, Human, Recombinant

10125-HNAE

Expression host: E. coli

Human IL-1F5 Protein 8427

IL36RN Protein, Mouse, Recombinant

50213-MNAE

Expression host: E. coli

Mouse IL-1F5 Protein 15116
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IL36RN Antibody (8)

Application Clonality
Host

Anti-IL36RN Antibody

50213-T24

Specificity: Mouse

Application: ELISA,IHC-P

Clonality: PAb

Mouse IL-1F5 Immunohistochemistry(IHC) 15241

Anti-IL36RN Antibody

10125-RP01

Specificity: Human

Application: ELISA

Clonality: PAb

Anti-IL36RN Antibody

10125-T16

Specificity: Human

Application: ELISA

Clonality: PAb

Anti-IL36RN Antibody

10125-MM04

Specificity: Human

Application: ELISA

Clonality: MAb

Anti-IL36RN Antibody

10125-R002

Specificity: Human

Application: ELISA

Clonality: MAb

Anti-IL36RN Antibody

50213-T16

Specificity: Mouse

Application: ELISA

Clonality: PAb

Anti-IL36RN Antibody

50213-R022

Specificity: Mouse

Application: ELISA

Clonality: MAb

Anti-IL36RN Antibody

50213-RP01

Specificity: Mouse

Application: ELISA

Clonality: PAb

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IL36RN cDNA Clone (26)

Human
Mouse

IL36RN qPCR Primer (2)

Interleukin-1 family member 5 (IL-1F5), also known as interleukin 36 receptor antagonist (IL36RA), is a member of the interleukin 1 cytokine family. This cytokine was shown to specifically inhibit the activation of NF-kappaB induced by interleukin 1 family, member 6 (IL1F6). IL-1F5 is a highly and a specific antagonist of the IL-1 receptor-related protein 2-mediated response to interleukin 1 family member 9 (IL1F9). IL-1F5 could constitute part of an independent signaling system analogous to interleukin-1 alpha (IL-1A), beta (IL-1B) receptor agonist and interleukin-1 receptor type I (IL-1R1), which is present in epithelial barriers and takes part in local inflammatory response. It has been proved that IL-1F5 induces IL-4 mRNA and protein expression in glia in vitro and enhances hippocampal expression of IL-4 following intracerebroventricular injection. The inhibitory effect of IL-1F5 on LPS-induced IL-1β is attenuated in cells from IL-4-defective mice. Experiment results suggest that IL-1F5 mediates anti-inflammatory effects through its ability to induce IL-4 production and that this is a consequence of its interaction with the orphan receptor, single Ig IL-1R-related molecule (SIGIRR)/TIR8, as the effects were not observed in SIGIRR−/− mice. In contrast to its effects in brain tissue, IL-1F5 did not attenuate LPS-induced changes, or up-regulated IL-4 in macrophages or dendritic cells, suggesting that the effect is confined to the brain.
Protein
Antibody
Gene
qPCR
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