IL17RD (Protein|Antibody|cDNA Clone|ELISA Kit)

All IL17RD reagents are produced in house and quality controlled, including 5 IL17RD Antibody, 1 IL17RD ELISA, 13 IL17RD Gene, 3 IL17RD Lysate, 3 IL17RD Protein, 1 IL17RD qPCR. All IL17RD reagents are ready to use.

Recombinant IL17RD proteins are expressed by HEK293 Cells with fusion tags as C-His, C-human IgG1-Fc.

IL17RDantibodies are validated with different applications, which are ELISA, ELISA(Cap).

IL17RDcDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each IL17RD of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.

IL17RDELISA Kit are quality controlled by 8 internation QC standard which guarantee every ELISA Kit with high quality.

IL17RD Protein (3)

Species

IL17RD Protein, Human, Recombinant (His Tag)

10507-H08H

Expression host: HEK293 Cells

Human IL-17RD Protein 8876

IL17RD Protein, Canine, Recombinant (His Tag)

70104-D08H

Expression host: HEK293 Cells

Canine IL-17RD Protein 12291

IL17RD Protein, Canine, Recombinant (Fc Tag)

70104-D02H

Expression host: HEK293 Cells

Canine IL-17RD Protein 12290
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IL17RD Antibody (5)

Application Clonality
Host

Anti-IL17RD Antibody

10507-R001

Application: ELISA(Cap)

Clonality: MAb

Anti-IL17RD Antibody

10507-RP01

Application: ELISA

Clonality: PAb

Anti-IL17RD Antibody

10507-RP02

Application: ELISA

Clonality: PAb

Anti-IL17RD Antibody

10507-R010

Application: ELISA

Clonality: MAb

Anti-IL17RD Antibody

70104-T16

Application: ELISA

Clonality: PAb

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IL17RD ELISA KIT & match antibody elias pair set ( 1 )

IL17RD Matched ELISA Antibody Pair Set,Human

SEK10507

Assay Range: 78.125 pg/ml

Human IL-17RD ELISA Pair Set Standard Curve 13846

IL17RD cDNA Clone (13)

Human

IL17RD qPCR Primer (1)

IL17RD Lysate (3)

Interleukin-17 receptor D (IL-17D) also known as Interleukin-17 receptor-like protein, is a member of interleukine-17 recepter family. IL-17RD functions as a feedback inhibitor of fibroblast growth factor mediated Ras-MAPK signaling and ERK activation. It may inhibit FGF-induced FGFR1 tyrosine phosphorylation, regulate the nuclear ERK signaling pathway by spatially blocking nuclear translocation of activated ERK By similarity, and mediate JNK activation and may be involved in apoptosis. IL-17RD is found expressed in the neopallial cortex, rhombic lip and dorsal regions of the myelencephalon and in the frontal nasal process. IL-17RD is also expressed in the commissural plate and septal area of the forebrain and in the hippocampus, lens and optic cup. In the oral region, IL-17RD is expressed in the tongue and in the mesenchyme of the first branchial arch. It is also expressed in the developing inner ear. IL-17RD interacts with both IL-17R-Myc and IL-17RB-Myc. Both the intracellular and extracellular domains of IL-17RD interact with IL-17R. IL-17R forms a heteromeric complex with IL-17RD. Experiment results indicate that IL-17RD is able to affect IL-17R localization, suggesting that these two molecules are colocalized and associate with each other within cells. The fact that IL-17RD Delta ICD is unable to mediate IL-17 signaling but functions as a dominant-negative form indicates that the intracellular domain of IL-17RD is pivotal. In addition, IL-17RD interacts with the IL-17R downstream molecule TRAF6. It has been proposed that the IL-17RD intracellular domain interacts with IL-17R and TRAF6 to deliver the downstream signal.

Protein
Antibody
ELISA
Gene
qPCR
Lysate
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