IL-17R / IL-17RA Protein & Antibody (CD217)

Interleukin 17 Receptor A (Cluster of Differentiation 217)

IL-17R Products

IL-17R Protein, Recombinant

Molecule	Species	Description	Cat. No
IL-17R/IL-17RA/CD217	Human	IL-17R/IL-17RA/CD217 Protein, Recombinant	10895-H03H
IL-17R/IL-17RA/CD217	Human	IL-17R/IL-17RA/CD217 Protein, Recombinant	10895-H08H
IL-17R/IL-17RA/CD217	Mouse	IL-17R/IL-17RA/CD217 Protein, Recombinant	50328-M08H

  10895-H03H:  Measured by its ability to bind human IL17F in a functional Elisa.

IL-17R Antibody Products

Molecule	Application	Description	Cat. No
Human IL-17R/IL-17RA/CD217	ELISA	IL-17R/IL-17RA/CD217 Antibody, Mouse MAb	10895-MM06
Human IL-17R/IL-17RA/CD217	WB	IL-17R/IL-17RA/CD217 Antibody, Mouse MAb	10895-MM07
Human IL-17R/IL-17RA/CD217	WB, ELISA	IL7RA / CD127 Antibody	10895-RP01
Human IL-17R/IL-17RA/CD217	WB, ELISA	IL7RA / CD127 Antibody (Antigen Affinity Purified)	10895-RP02
Human IL-17R/IL-17RA/CD217	WB, ELISA	IL-17R/IL-17RA/CD217 Antibody, Rabbit MAb	10895-R012
Mouse IL-17R/IL-17RA/CD217	WB, ELISA	IL-17R / IL-17RA Antibody (Antigen Affinity Purified)	50328-RP02

IL-17R ELISA Kit

Molecule	Application	Description	Cat. No
Human IL-17R/IL-17RA/CD217	ELISA	IL-17R/IL-17RA/CD217 ELISA Kit	SEK10895

IL-17R cDNA Clone

Molecule	Species	Description	Cat. No
IL-17R/IL-17RA/CD217	Human	Homo sapiens IL-17R/IL-17RA/CD217 cDNA Clone(NM_014339.4)	HG10895-M
IL-17R/IL-17RA/CD217	Mouse	Mus musculus IL-17R/IL-17RA/CD217 cDNA Clone	MG50328-M
IL-17R/IL-17RA/CD217	Rat	Rat IL-17R/IL-17RA/CD217 cDNA Clone	RG80190-G
IL-17R/IL-17RA/CD217	Cynomolgus	Cynomolgus monkey IL17RA cDNA Clone / ORF Clone	KG90127-G

IL-17R Related Areas

Immunology>>Cytokine & Receptor>>Interleukin & Receptor>>IL-17 Family & IL-17 Receptor Family>>IL-17R/IL-17RA/CD217

Immunology>>Cluster of Differentiation>>T Cell CD Antigen>>Helper T Cells / Regulatory T Cells>>IL-17R/IL-17RA/CD217

IL-17R Alternative Names

IL-17R, CD217, IL17RA, CDw217, IL17R, MGC10262, hIL-17R [Homo sapiens]

Il17ra, Il17r, Cdw217, AW538159, VDw217 [Mus musculus]

IL-17R Background

Interleukin-17 receptor (IL-17R), also known as Interleukin-17 receptor A (IL-17RA) and CD217 antigen (CD217), is a cytokine receptor which binds interleukin 17. IL-17R/IL-17RA (CD217) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. IL-17R/IL-17RA (CD217) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor IL-17RA play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Defects in IL-17R/IL-17RA (CD217) are the cause of familial candidiasis type 5 (CANDF5). CANDF5 is a rare disorder with altered immune responses and impaired clearance of fungal infections, selective against Candida. It is characterized by persistent and/or recurrent infections of the skin, nails and mucous membranes caused by organisms of the genus Candida, mainly Candida albicans.

IL-17R Related Studies

1. Gaffen SL. (2009) Structure and signalling in the IL-17 receptor family. Nat Rev Immunol. 9 (8): 556-67.
2. Johansen C, et al.. (2009) Characterization of the interleukin-17 isoforms and receptors in lesional psoriatic skin. Br J Dermatol. 160 (2): 319-24.
3. Yao Z, et al.. (1997) Molecular characterization of the human interleukin (IL)-17 receptor. Cytokine 9 (11): 794-800.