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IL17RA/IL-17RA/CD217 Rabbit MAb

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    Human IL17RA Antibody Product Information
    Immunogen:Recombinant Human IL17RA protein (Catalog#10895-H08H)
    Clone ID:012
    Ig Type:Rabbit IgG
    Concentration:
    Formulation:0.2 μm filtered solution in PBS
    Preparation:This antibody was obtained from a rabbit immunized with purified, recombinant Human IL17RA (rh IL17RA; Catalog#10895-H08H; NP_055154.3; Met 1-Trp 320).
    Other IL17RA Antibody Products
    Reactivity: Human  
    Application: ELISA  
      10895-RP01-200
      10895-RP01-100
      10895-RP01-400
      200 µg 
      100 µg 
       
      Add to Cart
      Reactivity: Human  
      Application: ELISA  
        10895-MM06-50
        10895-MM06-100
        10895-MM06-200
        50 µg 
        100 µg 
        200 µg 
        Add to Cart
        Reactivity: Human  
        Application: WB  
        • Slide 1
        10895-MM07-50
        10895-MM07-100
        10895-MM07-200
        50 µg 
        100 µg 
        200 µg 
        Add to Cart
        Reactivity: Human  
        Application: B/N  
        • Slide 1
        10895-R004-500
        10895-R004-200
        500 µg 
        200 µg 
        Add to Cart
        Reactivity: Human  
        Application: ELISA  
          10895-T16-100
          10895-T16-50
          10895-T16-200
          100 µg 
          50 µg 
          200 µg 
          Add to Cart
          Reactivity: Mouse  
          Application: ELISA  
            50328-RP02-200
            50328-RP02-50
            50328-RP02-100
            200 µg 
            50 µg 
            100 µg 
            Add to Cart
            Reactivity: Rat  
            Application: ELISA  
              80190-MM05-100
              80190-MM05-50
              80190-MM05-200
              100 µg 
              50 µg 
              200 µg 
              Add to Cart
              Reactivity: Rat  
              Application: ELISA  
                80190-RP01-100
                80190-RP01-200
                80190-RP01-400
                100 µg 
                200 µg 
                 
                Add to Cart
                Reactivity: Rat  
                Application: ELISA  
                  80190-T16-50
                  80190-T16-100
                  80190-T16-200
                  50 µg 
                  100 µg 
                  200 µg 
                  Add to Cart
                  IL17RA/IL-17RA/CD217 Background

                  Interleukin-17 receptor (IL-17R), also known as Interleukin-17 receptor A (IL-17RA) and CD217 antigen (CD217), is a cytokine receptor which binds interleukin 17. IL-17R/IL-17RA (CD217) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. IL-17R/IL-17RA (CD217) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor IL-17RA play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Defects in IL-17R/IL-17RA (CD217) are the cause of familial candidiasis type 5 (CANDF5). CANDF5 is a rare disorder with altered immune responses and impaired clearance of fungal infections, selective against Candida. It is characterized by persistent and/or recurrent infections of the skin, nails and mucous membranes caused by organisms of the genus Candida, mainly Candida albicans.

                  Human IL17RA/IL-17RA/CD217 References
                • Gaffen SL. (2009) Structure and signalling in the IL-17 receptor family. Nat Rev Immunol. 9 (8): 556-67.
                • Johansen C, et al.. (2009) Characterization of the interleukin-17 isoforms and receptors in lesional psoriatic skin. Br J Dermatol. 160 (2): 319-24.
                • Yao Z, et al.. (1997) Molecular characterization of the human interleukin (IL)-17 receptor. Cytokine 9 (11): 794-800.
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                  Size / Price
                  Catalog: 10895-R012-50
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                  Datasheet & Documentation

                  All information of our products is subject to change without notice. Please refer to COA enclosed in shipped package for the newest information.
                  Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"