All IL-15 reagents are produced in house and quality controlled, including 6 IL-15 Antibody, 1 IL-15 ELISA, 52 IL-15 Gene, 3 IL-15 Protein, 3 IL-15 qPCR. All IL-15 reagents are ready to use.
Recombinant IL-15 proteins are expressed by E. coli with fusion tags as Native, N-His, N-cleavage.
IL-15antibodies are validated with different applications, which are WB, ELISA, ELISA(Det), ELISA(Cap).
IL-15cDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each IL-15 of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.
IL-15ELISA Kit are quality controlled by 8 internation QC standard which guarantee every ELISA Kit with high quality.
The protein encoded by IL15 gene is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between this cytokine and IL2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. Studies of the mouse counterpart suggested that this cytokine may increase the expression of apoptosis inhibitor BCL2L1/BCL-x(L), possibly through the transcription activation activity of STAT6, and thus prevent apoptosis. Alternatively spliced transcript variants of this gene have been reported.